Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation

12 plant species traditionally used by the Mapuche people in Chile to treat wounds and inflammations have been evaluated for their direct blood platelet inhibition. Seven of the 12 tested plant species showed platelet inhibitory effect in sheep blood, and four of these were also able to inhibit the...

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Autores principales: Falkenberg, Susan Skanderup, Tarnow, Inge, Guzman, Alfonso, Mølgaard, Per, Simonsen, Henrik Toft
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199090/
https://www.ncbi.nlm.nih.gov/pubmed/22028732
http://dx.doi.org/10.1155/2012/647620
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author Falkenberg, Susan Skanderup
Tarnow, Inge
Guzman, Alfonso
Mølgaard, Per
Simonsen, Henrik Toft
author_facet Falkenberg, Susan Skanderup
Tarnow, Inge
Guzman, Alfonso
Mølgaard, Per
Simonsen, Henrik Toft
author_sort Falkenberg, Susan Skanderup
collection PubMed
description 12 plant species traditionally used by the Mapuche people in Chile to treat wounds and inflammations have been evaluated for their direct blood platelet inhibition. Seven of the 12 tested plant species showed platelet inhibitory effect in sheep blood, and four of these were also able to inhibit the ADP- (5.0 μM) and collagen- (2.0 μg/mL) induced aggregations in human blood. These four species in respective extracts (in brackets) were Blechnum chilense (MeOH), Luma apiculata (H(2)O), Amomyrtus luma (DCM : MeOH 1 : 1) and Cestrum parqui (DCM : MeOH 1 : 1). The platelet aggregating inhibitory effects of A. luma (DCM : MeOH 1 : 1), and L. apiculata (H(2)O) were substantial and confirmed by inhibition of platelet surface activation markers.
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spelling pubmed-31990902011-10-25 Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation Falkenberg, Susan Skanderup Tarnow, Inge Guzman, Alfonso Mølgaard, Per Simonsen, Henrik Toft Evid Based Complement Alternat Med Research Article 12 plant species traditionally used by the Mapuche people in Chile to treat wounds and inflammations have been evaluated for their direct blood platelet inhibition. Seven of the 12 tested plant species showed platelet inhibitory effect in sheep blood, and four of these were also able to inhibit the ADP- (5.0 μM) and collagen- (2.0 μg/mL) induced aggregations in human blood. These four species in respective extracts (in brackets) were Blechnum chilense (MeOH), Luma apiculata (H(2)O), Amomyrtus luma (DCM : MeOH 1 : 1) and Cestrum parqui (DCM : MeOH 1 : 1). The platelet aggregating inhibitory effects of A. luma (DCM : MeOH 1 : 1), and L. apiculata (H(2)O) were substantial and confirmed by inhibition of platelet surface activation markers. Hindawi Publishing Corporation 2012 2011-10-20 /pmc/articles/PMC3199090/ /pubmed/22028732 http://dx.doi.org/10.1155/2012/647620 Text en Copyright © 2012 Susan Skanderup Falkenberg et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Falkenberg, Susan Skanderup
Tarnow, Inge
Guzman, Alfonso
Mølgaard, Per
Simonsen, Henrik Toft
Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation
title Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation
title_full Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation
title_fullStr Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation
title_full_unstemmed Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation
title_short Mapuche Herbal Medicine Inhibits Blood Platelet Aggregation
title_sort mapuche herbal medicine inhibits blood platelet aggregation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199090/
https://www.ncbi.nlm.nih.gov/pubmed/22028732
http://dx.doi.org/10.1155/2012/647620
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