Multimodal Stepped Care Approach Involving Topical Analgesics for Severe Intractable Neuropathic Pain in CRPS Type 1: A Case Report

A multimodal stepped care approach has been successfully applied to a patient with complex regional pain syndrome type 1 and severe intractable pain, not responding to regular neuropathic pain medication. The choice to administer drugs in creams was made because of the intolerable adverse effects to...

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Detalles Bibliográficos
Autores principales: Kopsky, David J., Keppel Hesselink, Jan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199095/
https://www.ncbi.nlm.nih.gov/pubmed/22028723
http://dx.doi.org/10.1155/2011/319750
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author Kopsky, David J.
Keppel Hesselink, Jan M.
author_facet Kopsky, David J.
Keppel Hesselink, Jan M.
author_sort Kopsky, David J.
collection PubMed
description A multimodal stepped care approach has been successfully applied to a patient with complex regional pain syndrome type 1 and severe intractable pain, not responding to regular neuropathic pain medication. The choice to administer drugs in creams was made because of the intolerable adverse effects to oral medication. With this method, peak-dose adverse effects did not occur. The multimodal stepped care approach resulted in considerable and clinically relevant decrease in pain after every step, using topical amitriptyline, ketamine, and dimethylsulphoxide.
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spelling pubmed-31990952011-10-25 Multimodal Stepped Care Approach Involving Topical Analgesics for Severe Intractable Neuropathic Pain in CRPS Type 1: A Case Report Kopsky, David J. Keppel Hesselink, Jan M. Case Rep Med Case Report A multimodal stepped care approach has been successfully applied to a patient with complex regional pain syndrome type 1 and severe intractable pain, not responding to regular neuropathic pain medication. The choice to administer drugs in creams was made because of the intolerable adverse effects to oral medication. With this method, peak-dose adverse effects did not occur. The multimodal stepped care approach resulted in considerable and clinically relevant decrease in pain after every step, using topical amitriptyline, ketamine, and dimethylsulphoxide. Hindawi Publishing Corporation 2011 2011-10-17 /pmc/articles/PMC3199095/ /pubmed/22028723 http://dx.doi.org/10.1155/2011/319750 Text en Copyright © 2011 D. J. Kopsky and J. M. Keppel Hesselink. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kopsky, David J.
Keppel Hesselink, Jan M.
Multimodal Stepped Care Approach Involving Topical Analgesics for Severe Intractable Neuropathic Pain in CRPS Type 1: A Case Report
title Multimodal Stepped Care Approach Involving Topical Analgesics for Severe Intractable Neuropathic Pain in CRPS Type 1: A Case Report
title_full Multimodal Stepped Care Approach Involving Topical Analgesics for Severe Intractable Neuropathic Pain in CRPS Type 1: A Case Report
title_fullStr Multimodal Stepped Care Approach Involving Topical Analgesics for Severe Intractable Neuropathic Pain in CRPS Type 1: A Case Report
title_full_unstemmed Multimodal Stepped Care Approach Involving Topical Analgesics for Severe Intractable Neuropathic Pain in CRPS Type 1: A Case Report
title_short Multimodal Stepped Care Approach Involving Topical Analgesics for Severe Intractable Neuropathic Pain in CRPS Type 1: A Case Report
title_sort multimodal stepped care approach involving topical analgesics for severe intractable neuropathic pain in crps type 1: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199095/
https://www.ncbi.nlm.nih.gov/pubmed/22028723
http://dx.doi.org/10.1155/2011/319750
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AT keppelhesselinkjanm multimodalsteppedcareapproachinvolvingtopicalanalgesicsforsevereintractableneuropathicpainincrpstype1acasereport

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