Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile

Putative cancer stem cells have been identified in glioblastomas and are associated with radio- and chemo-resistance. Further knowledge about these cells is thus highly warranted for the development of better glioblastoma therapies. Gene expression analyses of 11 high-grade glioma cultures identifie...

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Detalles Bibliográficos
Autores principales: Hägerstrand, Daniel, He, Xiaobing, Bradic Lindh, Maja, Hoefs, Saskia, Hesselager, Göran, Östman, Arne, Nistér, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199157/
https://www.ncbi.nlm.nih.gov/pubmed/21940738
http://dx.doi.org/10.1093/neuonc/nor113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199157/
https://www.ncbi.nlm.nih.gov/pubmed/21940738
http://dx.doi.org/10.1093/neuonc/nor113

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