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Attenuation of antigen-induced airway hyperresponsiveness and inflammation in CXCR3 knockout mice

BACKGROUND: CD8+ T cells participate in airway hyperresponsiveness (AHR) and allergic pulmonary inflammation that are characteristics of asthma. CXCL10 by binding to CXCR3 expressed preferentially on activated CD8+ T cells, attracts T cells homing to the lung. We studied the contribution and limitat...

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Detalles Bibliográficos
Autores principales:	Lin, Yi, Yan, Haibo, Xiao, Yu, Piao, Hongmei, Xiang, Ruolan, Jiang, Lei, Chen, Huaxia, Huang, Kewu, Guo, Zijian, Zhou, Wexun, Lu, Bao, Gao, Jinming
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199245/ https://www.ncbi.nlm.nih.gov/pubmed/21939519 http://dx.doi.org/10.1186/1465-9921-12-123

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