Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: One step forward, and one step back?

A group of 160 patients with primary glioblastoma treated with radiotherapy and temozolomide was analyzed for the impact of O6-methly-guanly-methyl-transferase (MGMT)-promoter methylation as well as isocitrate dehydrogenase (IDH)1-mutational status. Unexpectedly, overall survival or progression-free...

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Detalles Bibliográficos
Autores principales: Combs, Stephanie E, Rieken, Stefan, Wick, Wolfgang, Abdollahi, Amir, von Deimling, Andreas, Debus, Jürgen, Hartmann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199258/
https://www.ncbi.nlm.nih.gov/pubmed/21910919
http://dx.doi.org/10.1186/1748-717X-6-115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199258/
https://www.ncbi.nlm.nih.gov/pubmed/21910919
http://dx.doi.org/10.1186/1748-717X-6-115

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