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Two-pore Channels Form Homo- and Heterodimers

Two-pore channels (TPCs) have been recently identified as NAADP-regulated Ca(2+) release channels, which are localized on the endolysosomal system. TPCs have a 12-transmembrane domain (TMD) structure and are evolutionary intermediates between the 24-TMD α-subunits of Na(+) or Ca(2+) channels and the...

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Detalles Bibliográficos
Autores principales:	Rietdorf, Katja, Funnell, Tim M., Ruas, Margarida, Heinemann, Jennifer, Parrington, John, Galione, Antony
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2011
Materias:	Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199452/ https://www.ncbi.nlm.nih.gov/pubmed/21903581 http://dx.doi.org/10.1074/jbc.C111.289835

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