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L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission

Dyskinesia is a serious motor complication caused by prolonged administration of l-DOPA to patients affected by Parkinson’s disease. Accumulating evidence indicates that l-DOPA-induced dyskinesia (LID) is primarily caused by the development of sensitized dopamine D1 receptor (D1R) transmission in th...

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Detalles Bibliográficos
Autores principales:	Feyder, Michael, Bonito-Oliva, Alessandra, Fisone, Gilberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2011
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199545/ https://www.ncbi.nlm.nih.gov/pubmed/22028687 http://dx.doi.org/10.3389/fnbeh.2011.00071

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