Apical membrane rupture and backward bile flooding in acetaminophen-induced hepatocyte necrosis

Morphological changes of hepatocyte death have so far only been described on cells in culture or in tissue sections. Using a high-resolution and high-magnification multiphoton microscopic system, we recorded in living mice serial changes of acetaminophen (APAP)-induced hepatocyte necrosis in relevan...

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Detalles Bibliográficos
Autores principales: Li, F-C, Huang, G-T, Lin, C-J, Wang, S-S, Sun, T-L, Lo, S-Y, Lo, W, Chiou, L-L, Dong, C-Y, Lee, H-S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199717/
https://www.ncbi.nlm.nih.gov/pubmed/21776021
http://dx.doi.org/10.1038/cddis.2011.68

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