Cargando…

Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation

Cisplatin is widely used for treating various solid tumors. However, this drug produces dose-limiting ototoxicity and nephrotoxicity, which significantly reduce the quality of life of cancer patients. While nephrotoxicity could be alleviated by diuresis, there is currently no approved treatment for...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kaur, T, Mukherjea, D, Sheehan, K, Jajoo, S, Rybak, L P, Ramkumar, V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199718/ https://www.ncbi.nlm.nih.gov/pubmed/21776018 http://dx.doi.org/10.1038/cddis.2011.63

Ejemplares similares

Oxidative Stress and Inflammation Caused by Cisplatin Ototoxicity
por: Ramkumar, Vickram, et al.
Publicado: (2021)

Mechanisms of Cisplatin-Induced Ototoxicity and Otoprotection
por: Sheth, Sandeep, et al.
Publicado: (2017)

Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea
por: Bhatta, Puspanjali, et al.
Publicado: (2019)

Ototoxicity of Non-aminoglycoside Antibiotics
por: Rybak, Leonard P., et al.
Publicado: (2021)

Epigallocatechin-3-gallate, a prototypic chemopreventative agent for protection against cisplatin-based ototoxicity
por: Borse, Vikrant, et al.
Publicado: (2017)

Resveratrol Reduces Prostate Cancer Growth and Metastasis by Inhibiting the Akt/MicroRNA-21 Pathway
por: Sheth, Sandeep, et al.
Publicado: (2012)

The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss
por: Ghosh, Sumana, et al.
Publicado: (2018)

Targeting CXCL1 chemokine signaling for treating cisplatin ototoxicity
por: Al Aameri, Raheem F. H., et al.
Publicado: (2023)

Astaxanthine attenuates cisplatin ototoxicity in vitro and protects against cisplatin-induced hearing loss in vivo
por: Nan, Benyu, et al.
Publicado: (2022)

Dexmedetomidine Preconditioning Attenuates Cisplatin-Induced Ototoxicity in Zebrafish
por: Min, Too Jae, et al.
Publicado: (2014)

Oral Administration of Caffeine Exacerbates Cisplatin-Induced Hearing Loss
por: Sheth, Sandeep, et al.
Publicado: (2019)

The effectiveness of eugenol against cisplatin-induced ototoxicity()
por: Sakat, Muhammed Sedat, et al.
Publicado: (2018)

Cisplatin ototoxicity histopathology
por: Hodge, Sarah E., et al.
Publicado: (2021)

Protective Effect of Minocycline Against Cisplatin-induced Ototoxicity
por: Lee, Chi-Kyou, et al.
Publicado: (2011)

Protective Effect of Tempol against Cisplatin-Induced Ototoxicity
por: Youn, Cha Kyung, et al.
Publicado: (2016)

Protective effect of gallic acid against cisplatin-induced ototoxicity in rats()
por: Kilic, Korhan, et al.
Publicado: (2018)

The protective effects of whortleberry extract against cisplatin-induced ototoxicity in rats()
por: Özdemir, Doğukan, et al.
Publicado: (2017)

The role of apoptosis in cisplatin-induced ototoxicity in rats
por: De Freitas, Marcos Rabelo, et al.
Publicado: (2015)

Protective effect of berberine chloride against cisplatin-induced ototoxicity
por: Kim, Jong-Heun, et al.
Publicado: (2021)

The Effect of Dexpanthenol on Ototoxicity Induced by Cisplatin
por: Toplu, Yuksel, et al.
Publicado: (2016)

The Effects of Riluzole on Cisplatin-induced Ototoxicity
por: Üstün Bezgin, Selin, et al.
Publicado: (2019)

Mechanisms of Aminoglycoside- and Cisplatin-Induced Ototoxicity
por: Steyger, Peter S.
Publicado: (2021)

Regulator of G protein signaling 17 represents a novel target for treating cisplatin induced hearing loss
por: Dhukhwa, Asmita, et al.
Publicado: (2021)

Repositioning of Lansoprazole as a Protective Agent Against Cisplatin-Induced Ototoxicity
por: Wakai, Eri, et al.
Publicado: (2022)

Melatonin Attenuates Cisplatin-Induced Ototoxicity via Regulating the Cell Apoptosis of the Inner Ear
por: Wang, Na, et al.
Publicado: (2022)

Is Hyperbaric Oxygen Therapy Effective in Cisplatin-Induced Ototoxicity in Rats?
por: Cobanoglu, H. Bengu, et al.
Publicado: (2019)

Calpain mediated cisplatin-induced ototoxicity in mice
por: Chang, Liang, et al.
Publicado: (2013)

Otoprotective Effects of Zingerone on Cisplatin-Induced Ototoxicity
por: Lee, Chang Ho, et al.
Publicado: (2020)

Current Strategies to Combat Cisplatin-Induced Ototoxicity
por: Yu, Dehong, et al.
Publicado: (2020)

Mitophagy Impairment Aggravates Cisplatin-Induced Ototoxicity
por: Cho, Sung Il, et al.
Publicado: (2021)

Subclinical diagnosis of cisplatin-induced ototoxicity with biomarkers
por: Generotti, Charles, et al.
Publicado: (2022)

Telmisartan Attenuates Kanamycin-Induced Ototoxicity in Rats
por: Lee, Chang Ho, et al.
Publicado: (2021)

Possible Protective Effect of Sertraline against Cisplatin-Induced Ototoxicity: An Experimental Study
por: Ozturk, Murat, et al.
Publicado: (2013)

Ceramide-1-phosphate protection of cochlear hair cells against cisplatin ototoxicity
por: Le, Quang, et al.
Publicado: (2016)

Hydrogen Inhalation Protects against Ototoxicity Induced by Intravenous Cisplatin in the Guinea Pig
por: Fransson, Anette E., et al.
Publicado: (2017)

Cisplatin-Induced Ototoxicity in Rats Is Driven by RIP3-Dependent Necroptosis
por: Choi, Mi-Jin, et al.
Publicado: (2019)

Cisplatin-Associated Ototoxicity: A Review for the Health Professional
por: Paken, Jessica, et al.
Publicado: (2016)

The genetic vulnerability to cisplatin ototoxicity: a systematic review
por: Tserga, Evangelia, et al.
Publicado: (2019)

Cisplatin-Induced Ototoxicity: Effects, Mechanisms and Protection Strategies
por: Callejo, Angela, et al.
Publicado: (2015)

Supporting Cells and Their Potential Roles in Cisplatin-Induced Ototoxicity
por: Waissbluth, Sofia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_97ka44p6rs14uarh6gv04bcqjl