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Age-dependent decrease in glutamine synthetase expression in the hippocampal astroglia of the triple transgenic Alzheimer's disease mouse model: mechanism for deficient glutamatergic transmission?

Astrocytes are fundamental for brain homeostasis and the progression and outcome of many neuropathologies including Alzheimer's disease (AD). In the triple transgenic mouse model of AD (3xTg-AD) generalised hippocampal astroglia atrophy precedes a restricted and specific β-amyloid (Aβ) plaque-r...

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Detalles Bibliográficos
Autores principales:	Olabarria, Markel, Noristani, Harun N, Verkhratsky, Alexei, Rodríguez, José J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199854/ https://www.ncbi.nlm.nih.gov/pubmed/21801442 http://dx.doi.org/10.1186/1750-1326-6-55

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