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Improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods

BACKGROUND: Patients with hypertension continue to have less than optimal blood pressure control, with nearly one in five Canadian adults having hypertension. Pharmacist prescribing is gaining favor as a potential clinically efficacious and cost-effective means to improve both access and quality of...

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Autores principales: Charrois, Theresa L, McAlister, Finlay A, Cooney, Dale, Lewanczuk, Richard, Kolber, Michael R, Campbell, Norman RC, Rosenthal, Meagen, Houle, Sherilyn KD, Tsuyuki, Ross T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199859/
https://www.ncbi.nlm.nih.gov/pubmed/21834970
http://dx.doi.org/10.1186/1748-5908-6-94
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author Charrois, Theresa L
McAlister, Finlay A
Cooney, Dale
Lewanczuk, Richard
Kolber, Michael R
Campbell, Norman RC
Rosenthal, Meagen
Houle, Sherilyn KD
Tsuyuki, Ross T
author_facet Charrois, Theresa L
McAlister, Finlay A
Cooney, Dale
Lewanczuk, Richard
Kolber, Michael R
Campbell, Norman RC
Rosenthal, Meagen
Houle, Sherilyn KD
Tsuyuki, Ross T
author_sort Charrois, Theresa L
collection PubMed
description BACKGROUND: Patients with hypertension continue to have less than optimal blood pressure control, with nearly one in five Canadian adults having hypertension. Pharmacist prescribing is gaining favor as a potential clinically efficacious and cost-effective means to improve both access and quality of care. With Alberta being the first province in Canada to have independent prescribing by pharmacists, it offers a unique opportunity to evaluate outcomes in patients who are prescribed antihypertensive therapy by pharmacists. METHODS: The study is a randomized controlled trial of enhanced pharmacist care, with the unit of randomization being the patient. Participants will be randomized to enhanced pharmacist care (patient identification, assessment, education, close follow-up, and prescribing/titration of antihypertensive medications) or usual care. Participants are patients in rural Alberta with undiagnosed/uncontrolled blood pressure, as defined by the Canadian Hypertension Education Program. The primary outcome is the change in systolic blood pressure between baseline and 24 weeks in the enhanced-care versus usual-care arms. There are also three substudies running in conjunction with the project examining different remuneration models, investigating patient knowledge, and assessing health-resource utilization amongst patients in each group. DISCUSSION: To date, one-third of the required sample size has been recruited. There are 15 communities and 17 pharmacists actively screening, recruiting, and following patients. This study will provide high-level evidence regarding pharmacist prescribing. TRIAL REGISTRATION: Clinicaltrials.gov NCT00878566.
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spelling pubmed-31998592011-10-25 Improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods Charrois, Theresa L McAlister, Finlay A Cooney, Dale Lewanczuk, Richard Kolber, Michael R Campbell, Norman RC Rosenthal, Meagen Houle, Sherilyn KD Tsuyuki, Ross T Implement Sci Study Protocol BACKGROUND: Patients with hypertension continue to have less than optimal blood pressure control, with nearly one in five Canadian adults having hypertension. Pharmacist prescribing is gaining favor as a potential clinically efficacious and cost-effective means to improve both access and quality of care. With Alberta being the first province in Canada to have independent prescribing by pharmacists, it offers a unique opportunity to evaluate outcomes in patients who are prescribed antihypertensive therapy by pharmacists. METHODS: The study is a randomized controlled trial of enhanced pharmacist care, with the unit of randomization being the patient. Participants will be randomized to enhanced pharmacist care (patient identification, assessment, education, close follow-up, and prescribing/titration of antihypertensive medications) or usual care. Participants are patients in rural Alberta with undiagnosed/uncontrolled blood pressure, as defined by the Canadian Hypertension Education Program. The primary outcome is the change in systolic blood pressure between baseline and 24 weeks in the enhanced-care versus usual-care arms. There are also three substudies running in conjunction with the project examining different remuneration models, investigating patient knowledge, and assessing health-resource utilization amongst patients in each group. DISCUSSION: To date, one-third of the required sample size has been recruited. There are 15 communities and 17 pharmacists actively screening, recruiting, and following patients. This study will provide high-level evidence regarding pharmacist prescribing. TRIAL REGISTRATION: Clinicaltrials.gov NCT00878566. BioMed Central 2011-08-11 /pmc/articles/PMC3199859/ /pubmed/21834970 http://dx.doi.org/10.1186/1748-5908-6-94 Text en Copyright ©2011 Charrois et al; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Study Protocol
Charrois, Theresa L
McAlister, Finlay A
Cooney, Dale
Lewanczuk, Richard
Kolber, Michael R
Campbell, Norman RC
Rosenthal, Meagen
Houle, Sherilyn KD
Tsuyuki, Ross T
Improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods
title Improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods
title_full Improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods
title_fullStr Improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods
title_full_unstemmed Improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods
title_short Improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods
title_sort improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (rural rxaction): trial design and methods
topic Study Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199859/
https://www.ncbi.nlm.nih.gov/pubmed/21834970
http://dx.doi.org/10.1186/1748-5908-6-94
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