Inhibition of telomerase activity preferentially targets aldehyde dehydrogenase-positive cancer stem-like cells in lung cancer

BACKGROUND: Mortality rates for advanced lung cancer have not declined for decades, even with the implementation of novel chemotherapeutic regimens or the use of tyrosine kinase inhibitors. Cancer Stem Cells (CSCs) are thought to be responsible for resistance to chemo/radiotherapy. Therefore, target...

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Detalles Bibliográficos
Autores principales: Serrano, Diego, Bleau, Anne-Marie, Fernandez-Garcia, Ignacio, Fernandez-Marcelo, Tamara, Iniesta, Pilar, Ortiz-de-Solorzano, Carlos, Calvo, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3199900/
https://www.ncbi.nlm.nih.gov/pubmed/21827695
http://dx.doi.org/10.1186/1476-4598-10-96

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