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Future Perspectives: Therapeutic Targeting of Notch Signalling May Become a Strategy in Patients Receiving Stem Cell Transplantation for Hematologic Malignancies

The human Notch system consists of 5 ligands and 4 membrane receptors with promiscuous ligand binding, and Notch-initiated signalling interacts with a wide range of other intracellular pathways. The receptor signalling seems important for regulation of normal and malignant hematopoiesis, development...

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Detalles Bibliográficos
Autores principales:	Ersvaer, Elisabeth, Hatfield, Kimberley J., Reikvam, Håkon, Bruserud, Øystein
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200006/ https://www.ncbi.nlm.nih.gov/pubmed/22046566 http://dx.doi.org/10.1155/2011/570796

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