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Cancers of the Appendix: Review of the Literatures

Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of appendix are only 0.08% of all cancers and the treatment remains controversial. Here we...

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Autores principales: Ruoff, Carl, Hanna, Louay, Zhi, Wanqing, Shahzad, Ghulamullah, Gotlieb, Vladimir, Saif, Muhammad Wasif
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200132/
https://www.ncbi.nlm.nih.gov/pubmed/22084738
http://dx.doi.org/10.5402/2011/728579
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author Ruoff, Carl
Hanna, Louay
Zhi, Wanqing
Shahzad, Ghulamullah
Gotlieb, Vladimir
Saif, Muhammad Wasif
author_facet Ruoff, Carl
Hanna, Louay
Zhi, Wanqing
Shahzad, Ghulamullah
Gotlieb, Vladimir
Saif, Muhammad Wasif
author_sort Ruoff, Carl
collection PubMed
description Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of appendix are only 0.08% of all cancers and the treatment remains controversial. Here we are reporting a 46-year-old male presented with symptoms of appendicitis, diagnosed with adenocarcinoma of the appendix. The patient was treated with appendectomy and refused further surgical intervention to complete hemicolectomy. Up to date, he remains asymptomatic. We performed literature review of the tumors of the appendix. Most of the benign conditions are treated with surgery alone. Lymphomas require CHOP-like chemotherapy and carcinoid syndrome treatment with somatostatin analogues. It is generally recommended that right hemicolectomy is the preferred treatment for adenocarcinoma of appendix. The role of chemotherapy is unclear due to lacking randomized trials but seems to be accepted if there is lymph node involvement or peritoneal seeding.
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spelling pubmed-32001322011-11-14 Cancers of the Appendix: Review of the Literatures Ruoff, Carl Hanna, Louay Zhi, Wanqing Shahzad, Ghulamullah Gotlieb, Vladimir Saif, Muhammad Wasif ISRN Oncol Review Article Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of appendix are only 0.08% of all cancers and the treatment remains controversial. Here we are reporting a 46-year-old male presented with symptoms of appendicitis, diagnosed with adenocarcinoma of the appendix. The patient was treated with appendectomy and refused further surgical intervention to complete hemicolectomy. Up to date, he remains asymptomatic. We performed literature review of the tumors of the appendix. Most of the benign conditions are treated with surgery alone. Lymphomas require CHOP-like chemotherapy and carcinoid syndrome treatment with somatostatin analogues. It is generally recommended that right hemicolectomy is the preferred treatment for adenocarcinoma of appendix. The role of chemotherapy is unclear due to lacking randomized trials but seems to be accepted if there is lymph node involvement or peritoneal seeding. International Scholarly Research Network 2011 2011-08-11 /pmc/articles/PMC3200132/ /pubmed/22084738 http://dx.doi.org/10.5402/2011/728579 Text en Copyright © 2011 Carl Ruoff et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ruoff, Carl
Hanna, Louay
Zhi, Wanqing
Shahzad, Ghulamullah
Gotlieb, Vladimir
Saif, Muhammad Wasif
Cancers of the Appendix: Review of the Literatures
title Cancers of the Appendix: Review of the Literatures
title_full Cancers of the Appendix: Review of the Literatures
title_fullStr Cancers of the Appendix: Review of the Literatures
title_full_unstemmed Cancers of the Appendix: Review of the Literatures
title_short Cancers of the Appendix: Review of the Literatures
title_sort cancers of the appendix: review of the literatures
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200132/
https://www.ncbi.nlm.nih.gov/pubmed/22084738
http://dx.doi.org/10.5402/2011/728579
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