In vitro anti-plasmodial activity of Dicoma anomala subsp. gerrardii (Asteraceae): identification of its main active constituent, structure-activity relationship studies and gene expression profiling

BACKGROUND: Anti-malarial drug resistance threatens to undermine efforts to eliminate this deadly disease. The resulting omnipresent requirement for drugs with novel modes of action prompted a national consortium initiative to discover new anti-plasmodial agents from South African medicinal plants....

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Detalles Bibliográficos
Autores principales: Becker, John VW, van der Merwe, Marina M, van Brummelen, Anna C, Pillay, Pamisha, Crampton, Bridget G, Mmutlane, Edwin M, Parkinson, Chris, van Heerden, Fanie R, Crouch, Neil R, Smith, Peter J, Mancama, Dalu T, Maharaj, Vinesh J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200184/
https://www.ncbi.nlm.nih.gov/pubmed/21985233
http://dx.doi.org/10.1186/1475-2875-10-295

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