Proteomic Characterization of Cerebrospinal Fluid from Ataxia-Telangiectasia (A-T) Patients Using a LC/MS-Based Label-Free Protein Quantification Technology

Cerebrospinal fluid (CSF) has been used for biomarker discovery of neurodegenerative diseases in humans since biological changes in the brain can be seen in this biofluid. Inactivation of A-T-mutated protein (ATM), a multifunctional protein kinase, is responsible for A-T, yet biochemical studies hav...

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Detalles Bibliográficos
Autores principales: Dzieciatkowska, Monika, Qi, Guihong, You, Jinsam, Bemis, Kerry G., Sahm, Heather, Lederman, Howard M., Crawford, Thomas O., Gelbert, Lawrence M., Rothblum-Oviatt, Cynthia, Wang, Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200215/
https://www.ncbi.nlm.nih.gov/pubmed/22084690
http://dx.doi.org/10.1155/2011/578903

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