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Phosphorylation: The Molecular Switch of Double-Strand Break Repair
Repair of double-stranded breaks (DSBs) is vital to maintaining genomic stability. In mammalian cells, DSBs are resolved in one of the following complex repair pathways: nonhomologous end-joining (NHEJ), homologous recombination (HR), or the inclusive DNA damage response (DDR). These repair pathways...
Autores principales: | Summers, K. C., Shen, F., Sierra Potchanant, E. A., Phipps, E. A., Hickey, R. J., Malkas, L. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200257/ https://www.ncbi.nlm.nih.gov/pubmed/22084686 http://dx.doi.org/10.1155/2011/373816 |
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