Cargando…

Thrombospondin1 Deficiency Reduces Obesity-Associated Inflammation and Improves Insulin Sensitivity in a Diet-Induced Obese Mouse Model

BACKGROUND: Obesity is prevalent worldwide and is associated with insulin resistance. Advanced studies suggest that obesity-associated low-grade chronic inflammation contributes to the development of insulin resistance and other metabolic complications. Thrombospondin 1 (TSP1) is a multifunctional e...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yanzhang, Tong, Xiaopeng, Rumala, Courtney, Clemons, Kate, Wang, Shuxia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200349/
https://www.ncbi.nlm.nih.gov/pubmed/22039525
http://dx.doi.org/10.1371/journal.pone.0026656