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2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)phenol

The asymmetric unit of the title compound, C(20)H(15)N(3)O, contains two independent mol­ecules, each of which is disordered over two sets of sites corresponding to a rotation of approximately 180° of the dihydro­benzimidazoquinazoline moiety, with refined site occupancies of 0.7479 (13) and 0.2521 ...

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Autores principales: Eltayeb, Naser Eltaher, Teoh, Siang Guan, Quah, Ching Kheng, Fun, Hoong-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200611/
https://www.ncbi.nlm.nih.gov/pubmed/22058910
http://dx.doi.org/10.1107/S1600536811030583
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author Eltayeb, Naser Eltaher
Teoh, Siang Guan
Quah, Ching Kheng
Fun, Hoong-Kun
author_facet Eltayeb, Naser Eltaher
Teoh, Siang Guan
Quah, Ching Kheng
Fun, Hoong-Kun
author_sort Eltayeb, Naser Eltaher
collection PubMed
description The asymmetric unit of the title compound, C(20)H(15)N(3)O, contains two independent mol­ecules, each of which is disordered over two sets of sites corresponding to a rotation of approximately 180° of the dihydro­benzimidazoquinazoline moiety, with refined site occupancies of 0.7479 (13) and 0.2521 (12) for both mol­ecules. The pyrimidine rings are in sofa conformations. In one mol­ecule, the hy­droxy-substituted benzene ring forms dihedral angles of 83.9 (3) and 82.4 (4)° for the major and minor components, respectively, with the mean plane of the benzimidazole ring system. The corres­ponding dihedral angles in the other mol­ecule are 88.31 (14) and 85.8 (6)°. In the crystal, mol­ecules are linked via inter­molecular O—H⋯N and N—H.·O hydrogen bonds into chains along [100].
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spelling pubmed-32006112011-11-06 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)phenol Eltayeb, Naser Eltaher Teoh, Siang Guan Quah, Ching Kheng Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers The asymmetric unit of the title compound, C(20)H(15)N(3)O, contains two independent mol­ecules, each of which is disordered over two sets of sites corresponding to a rotation of approximately 180° of the dihydro­benzimidazoquinazoline moiety, with refined site occupancies of 0.7479 (13) and 0.2521 (12) for both mol­ecules. The pyrimidine rings are in sofa conformations. In one mol­ecule, the hy­droxy-substituted benzene ring forms dihedral angles of 83.9 (3) and 82.4 (4)° for the major and minor components, respectively, with the mean plane of the benzimidazole ring system. The corres­ponding dihedral angles in the other mol­ecule are 88.31 (14) and 85.8 (6)°. In the crystal, mol­ecules are linked via inter­molecular O—H⋯N and N—H.·O hydrogen bonds into chains along [100]. International Union of Crystallography 2011-08-06 /pmc/articles/PMC3200611/ /pubmed/22058910 http://dx.doi.org/10.1107/S1600536811030583 Text en © Eltayeb et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Eltayeb, Naser Eltaher
Teoh, Siang Guan
Quah, Ching Kheng
Fun, Hoong-Kun
2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)phenol
title 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)phenol
title_full 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)phenol
title_fullStr 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)phenol
title_full_unstemmed 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)phenol
title_short 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)phenol
title_sort 2-(5,6-dihydro­benzimidazo[1,2-c]quinazolin-6-yl)phenol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200611/
https://www.ncbi.nlm.nih.gov/pubmed/22058910
http://dx.doi.org/10.1107/S1600536811030583
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