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2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol
The asymmetric unit of the title compound, C(20)H(15)N(3)O, contains two independent molecules, each of which is disordered over two sets of sites corresponding to a rotation of approximately 180° of the dihydrobenzimidazoquinazoline moiety, with refined site occupancies of 0.7479 (13) and 0.2521 ...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200611/ https://www.ncbi.nlm.nih.gov/pubmed/22058910 http://dx.doi.org/10.1107/S1600536811030583 |
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author | Eltayeb, Naser Eltaher Teoh, Siang Guan Quah, Ching Kheng Fun, Hoong-Kun |
author_facet | Eltayeb, Naser Eltaher Teoh, Siang Guan Quah, Ching Kheng Fun, Hoong-Kun |
author_sort | Eltayeb, Naser Eltaher |
collection | PubMed |
description | The asymmetric unit of the title compound, C(20)H(15)N(3)O, contains two independent molecules, each of which is disordered over two sets of sites corresponding to a rotation of approximately 180° of the dihydrobenzimidazoquinazoline moiety, with refined site occupancies of 0.7479 (13) and 0.2521 (12) for both molecules. The pyrimidine rings are in sofa conformations. In one molecule, the hydroxy-substituted benzene ring forms dihedral angles of 83.9 (3) and 82.4 (4)° for the major and minor components, respectively, with the mean plane of the benzimidazole ring system. The corresponding dihedral angles in the other molecule are 88.31 (14) and 85.8 (6)°. In the crystal, molecules are linked via intermolecular O—H⋯N and N—H.·O hydrogen bonds into chains along [100]. |
format | Online Article Text |
id | pubmed-3200611 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-32006112011-11-06 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol Eltayeb, Naser Eltaher Teoh, Siang Guan Quah, Ching Kheng Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers The asymmetric unit of the title compound, C(20)H(15)N(3)O, contains two independent molecules, each of which is disordered over two sets of sites corresponding to a rotation of approximately 180° of the dihydrobenzimidazoquinazoline moiety, with refined site occupancies of 0.7479 (13) and 0.2521 (12) for both molecules. The pyrimidine rings are in sofa conformations. In one molecule, the hydroxy-substituted benzene ring forms dihedral angles of 83.9 (3) and 82.4 (4)° for the major and minor components, respectively, with the mean plane of the benzimidazole ring system. The corresponding dihedral angles in the other molecule are 88.31 (14) and 85.8 (6)°. In the crystal, molecules are linked via intermolecular O—H⋯N and N—H.·O hydrogen bonds into chains along [100]. International Union of Crystallography 2011-08-06 /pmc/articles/PMC3200611/ /pubmed/22058910 http://dx.doi.org/10.1107/S1600536811030583 Text en © Eltayeb et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Eltayeb, Naser Eltaher Teoh, Siang Guan Quah, Ching Kheng Fun, Hoong-Kun 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol |
title | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol |
title_full | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol |
title_fullStr | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol |
title_full_unstemmed | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol |
title_short | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol |
title_sort | 2-(5,6-dihydrobenzimidazo[1,2-c]quinazolin-6-yl)phenol |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200611/ https://www.ncbi.nlm.nih.gov/pubmed/22058910 http://dx.doi.org/10.1107/S1600536811030583 |
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