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2-Oxo-4-(thiophen-2-yl)-1,2,5,6-tetrahydrobenzo[h]quinoline-3-carbonitrile
In the molecule of the title compound, C(18)H(12)N(2)OS, the tetrahydrobenzo[h]quinoline fused-ring system is buckled owing to the ethylene –CH(2)CH(2)– fragment, the benzene ring and the pyridine ring being twisted by 16.0 (1)°. The 4-substituted aromatic ring is bent away from the pyridine rin...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200622/ https://www.ncbi.nlm.nih.gov/pubmed/22065622 http://dx.doi.org/10.1107/S1600536811033915 |
Sumario: | In the molecule of the title compound, C(18)H(12)N(2)OS, the tetrahydrobenzo[h]quinoline fused-ring system is buckled owing to the ethylene –CH(2)CH(2)– fragment, the benzene ring and the pyridine ring being twisted by 16.0 (1)°. The 4-substituted aromatic ring is bent away from the pyridine ring by 59.5 (2)° (for the major disordered thienyl component) in order to avoid crowding the cyanide substituent. In the crystal, two molecules are linked by a pair of N—H⋯O hydrogen bonds to form a centrosymmetric dimer. The thienyl ring is disordered over two sites in a 72.7 (2):27.3 ratio. |
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