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2-Oxo-4-(thio­phen-2-yl)-1,2,5,6-tetra­hydro­benzo[h]quinoline-3-carbonitrile

In the mol­ecule of the title compound, C(18)H(12)N(2)OS, the tetra­hydro­benzo[h]quinoline fused-ring system is buckled owing to the ethyl­ene –CH(2)CH(2)– fragment, the benzene ring and the pyridine ring being twisted by 16.0 (1)°. The 4-substituted aromatic ring is bent away from the pyridine rin...

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Autores principales: Asiri, Abdullah M., Faidallah, Hassan M., Al-Youbi, Abdulrahman O., Alamry, Khalid A., Ng, Seik Weng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200622/
https://www.ncbi.nlm.nih.gov/pubmed/22065622
http://dx.doi.org/10.1107/S1600536811033915
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author Asiri, Abdullah M.
Faidallah, Hassan M.
Al-Youbi, Abdulrahman O.
Alamry, Khalid A.
Ng, Seik Weng
author_facet Asiri, Abdullah M.
Faidallah, Hassan M.
Al-Youbi, Abdulrahman O.
Alamry, Khalid A.
Ng, Seik Weng
author_sort Asiri, Abdullah M.
collection PubMed
description In the mol­ecule of the title compound, C(18)H(12)N(2)OS, the tetra­hydro­benzo[h]quinoline fused-ring system is buckled owing to the ethyl­ene –CH(2)CH(2)– fragment, the benzene ring and the pyridine ring being twisted by 16.0 (1)°. The 4-substituted aromatic ring is bent away from the pyridine ring by 59.5 (2)° (for the major disordered thienyl component) in order to avoid crowding the cyanide substituent. In the crystal, two mol­ecules are linked by a pair of N—H⋯O hydrogen bonds to form a centrosymmetric dimer. The thienyl ring is disordered over two sites in a 72.7 (2):27.3 ratio.
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spelling pubmed-32006222011-11-06 2-Oxo-4-(thio­phen-2-yl)-1,2,5,6-tetra­hydro­benzo[h]quinoline-3-carbonitrile Asiri, Abdullah M. Faidallah, Hassan M. Al-Youbi, Abdulrahman O. Alamry, Khalid A. Ng, Seik Weng Acta Crystallogr Sect E Struct Rep Online Organic Papers In the mol­ecule of the title compound, C(18)H(12)N(2)OS, the tetra­hydro­benzo[h]quinoline fused-ring system is buckled owing to the ethyl­ene –CH(2)CH(2)– fragment, the benzene ring and the pyridine ring being twisted by 16.0 (1)°. The 4-substituted aromatic ring is bent away from the pyridine ring by 59.5 (2)° (for the major disordered thienyl component) in order to avoid crowding the cyanide substituent. In the crystal, two mol­ecules are linked by a pair of N—H⋯O hydrogen bonds to form a centrosymmetric dimer. The thienyl ring is disordered over two sites in a 72.7 (2):27.3 ratio. International Union of Crystallography 2011-08-27 /pmc/articles/PMC3200622/ /pubmed/22065622 http://dx.doi.org/10.1107/S1600536811033915 Text en © Asiri et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Asiri, Abdullah M.
Faidallah, Hassan M.
Al-Youbi, Abdulrahman O.
Alamry, Khalid A.
Ng, Seik Weng
2-Oxo-4-(thio­phen-2-yl)-1,2,5,6-tetra­hydro­benzo[h]quinoline-3-carbonitrile
title 2-Oxo-4-(thio­phen-2-yl)-1,2,5,6-tetra­hydro­benzo[h]quinoline-3-carbonitrile
title_full 2-Oxo-4-(thio­phen-2-yl)-1,2,5,6-tetra­hydro­benzo[h]quinoline-3-carbonitrile
title_fullStr 2-Oxo-4-(thio­phen-2-yl)-1,2,5,6-tetra­hydro­benzo[h]quinoline-3-carbonitrile
title_full_unstemmed 2-Oxo-4-(thio­phen-2-yl)-1,2,5,6-tetra­hydro­benzo[h]quinoline-3-carbonitrile
title_short 2-Oxo-4-(thio­phen-2-yl)-1,2,5,6-tetra­hydro­benzo[h]quinoline-3-carbonitrile
title_sort 2-oxo-4-(thio­phen-2-yl)-1,2,5,6-tetra­hydro­benzo[h]quinoline-3-carbonitrile
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200622/
https://www.ncbi.nlm.nih.gov/pubmed/22065622
http://dx.doi.org/10.1107/S1600536811033915
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