1-Benzoyl-3-[3-cyano-8-methyl-4-(1-methyl-1H-pyrrol-2-yl)-5,6,7,8-tetra­hydro­quinolin-2-yl]thio­urea

In the N-substituted benzoyl­thio­urea, C(24)H(23)N(5)OS, the benzoyl­thio­urea unit is non-planar (r.m.s. deviation = 0.126 Å). The aliphatic part of the tetra­hydro­quinoline fused-ring system is disordered over two positions in a 0.592 (5):0.408 (5) ratio. The pyridine and pyrrole rings are twist...

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Detalles Bibliográficos
Autores principales: Asiri, Abdullah M., Faidallah, Hassan M., Al-Youbi, Abdulrahman O., Alamry, Khalid A., Ng, Seik Weng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200694/
https://www.ncbi.nlm.nih.gov/pubmed/22064903
http://dx.doi.org/10.1107/S1600536811033046
Descripción
Sumario:In the N-substituted benzoyl­thio­urea, C(24)H(23)N(5)OS, the benzoyl­thio­urea unit is non-planar (r.m.s. deviation = 0.126 Å). The aliphatic part of the tetra­hydro­quinoline fused-ring system is disordered over two positions in a 0.592 (5):0.408 (5) ratio. The pyridine and pyrrole rings are twisted by 55.2 (1)° in order to avoid crowding of their respective substituents. Pairs of mol­ecules are linked by N—H⋯N hydrogen bonds, forming centrosymmetric dimers. Furthermore, an intra­molecular N—H⋯O hydrogen bond stabilizes the mol­ecular conformation.

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