N-{(2S)-3-Hy­droxy-4-[(5-methyl-1,3,4-thia­diazol-2-yl)sulfan­yl]-1-phenyl-2-but­yl}-4-methyl­benzene­sulfonamide

The thia­diazoyl and sulfonyl-benzene rings in the title compound, C(20)H(23)N(3)O(3)S(3), are aligned to the same side of the mol­ecule, forming a twisted ‘U’ shape [dihedral angle = 77.6 (5)°]. The benzyl-benzene ring is orientated in the opposite direction from the mol­ecule but projects approxim...

Descripción completa

Detalles Bibliográficos
Autores principales: Gomes, Claudia R. B., Vasconcelos, Thatyana R. A., Junior, Walcimar T. Vellasco, Cunico, Wilson, Wardell, James L., Wardell, Solange M. S. V., Tiekink, Edward R. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200695/
https://www.ncbi.nlm.nih.gov/pubmed/22064936
http://dx.doi.org/10.1107/S1600536811033575
_version_ 1782214728528953344
author Gomes, Claudia R. B.
Vasconcelos, Thatyana R. A.
Junior, Walcimar T. Vellasco
Cunico, Wilson
Wardell, James L.
Wardell, Solange M. S. V.
Tiekink, Edward R. T.
author_facet Gomes, Claudia R. B.
Vasconcelos, Thatyana R. A.
Junior, Walcimar T. Vellasco
Cunico, Wilson
Wardell, James L.
Wardell, Solange M. S. V.
Tiekink, Edward R. T.
author_sort Gomes, Claudia R. B.
collection PubMed
description The thia­diazoyl and sulfonyl-benzene rings in the title compound, C(20)H(23)N(3)O(3)S(3), are aligned to the same side of the mol­ecule, forming a twisted ‘U’ shape [dihedral angle = 77.6 (5)°]. The benzyl-benzene ring is orientated in the opposite direction from the mol­ecule but projects approximately along the same axis as the other rings [dihedral angle between benzene rings = 28.2 (5)°] so that, overall, the mol­ecule has a flattened shape. The hy­droxy and amine groups are almost syn which enables the formation of inter­molecular hy­droxy-OH⋯N(thia­diazo­yl) and amine-H⋯O(sulfon­yl) hydrogen bonds leading to a supra­molecular chain aligned along the a axis.
format Online
Article
Text
id pubmed-3200695
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-32006952011-11-06 N-{(2S)-3-Hy­droxy-4-[(5-methyl-1,3,4-thia­diazol-2-yl)sulfan­yl]-1-phenyl-2-but­yl}-4-methyl­benzene­sulfonamide Gomes, Claudia R. B. Vasconcelos, Thatyana R. A. Junior, Walcimar T. Vellasco Cunico, Wilson Wardell, James L. Wardell, Solange M. S. V. Tiekink, Edward R. T. Acta Crystallogr Sect E Struct Rep Online Organic Papers The thia­diazoyl and sulfonyl-benzene rings in the title compound, C(20)H(23)N(3)O(3)S(3), are aligned to the same side of the mol­ecule, forming a twisted ‘U’ shape [dihedral angle = 77.6 (5)°]. The benzyl-benzene ring is orientated in the opposite direction from the mol­ecule but projects approximately along the same axis as the other rings [dihedral angle between benzene rings = 28.2 (5)°] so that, overall, the mol­ecule has a flattened shape. The hy­droxy and amine groups are almost syn which enables the formation of inter­molecular hy­droxy-OH⋯N(thia­diazo­yl) and amine-H⋯O(sulfon­yl) hydrogen bonds leading to a supra­molecular chain aligned along the a axis. International Union of Crystallography 2011-08-27 /pmc/articles/PMC3200695/ /pubmed/22064936 http://dx.doi.org/10.1107/S1600536811033575 Text en © Gomes et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Gomes, Claudia R. B.
Vasconcelos, Thatyana R. A.
Junior, Walcimar T. Vellasco
Cunico, Wilson
Wardell, James L.
Wardell, Solange M. S. V.
Tiekink, Edward R. T.
N-{(2S)-3-Hy­droxy-4-[(5-methyl-1,3,4-thia­diazol-2-yl)sulfan­yl]-1-phenyl-2-but­yl}-4-methyl­benzene­sulfonamide
title N-{(2S)-3-Hy­droxy-4-[(5-methyl-1,3,4-thia­diazol-2-yl)sulfan­yl]-1-phenyl-2-but­yl}-4-methyl­benzene­sulfonamide
title_full N-{(2S)-3-Hy­droxy-4-[(5-methyl-1,3,4-thia­diazol-2-yl)sulfan­yl]-1-phenyl-2-but­yl}-4-methyl­benzene­sulfonamide
title_fullStr N-{(2S)-3-Hy­droxy-4-[(5-methyl-1,3,4-thia­diazol-2-yl)sulfan­yl]-1-phenyl-2-but­yl}-4-methyl­benzene­sulfonamide
title_full_unstemmed N-{(2S)-3-Hy­droxy-4-[(5-methyl-1,3,4-thia­diazol-2-yl)sulfan­yl]-1-phenyl-2-but­yl}-4-methyl­benzene­sulfonamide
title_short N-{(2S)-3-Hy­droxy-4-[(5-methyl-1,3,4-thia­diazol-2-yl)sulfan­yl]-1-phenyl-2-but­yl}-4-methyl­benzene­sulfonamide
title_sort n-{(2s)-3-hy­droxy-4-[(5-methyl-1,3,4-thia­diazol-2-yl)sulfan­yl]-1-phenyl-2-but­yl}-4-methyl­benzene­sulfonamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200695/
https://www.ncbi.nlm.nih.gov/pubmed/22064936
http://dx.doi.org/10.1107/S1600536811033575
work_keys_str_mv AT gomesclaudiarb n2s3hydroxy45methyl134thiadiazol2ylsulfanyl1phenyl2butyl4methylbenzenesulfonamide
AT vasconcelosthatyanara n2s3hydroxy45methyl134thiadiazol2ylsulfanyl1phenyl2butyl4methylbenzenesulfonamide
AT juniorwalcimartvellasco n2s3hydroxy45methyl134thiadiazol2ylsulfanyl1phenyl2butyl4methylbenzenesulfonamide
AT cunicowilson n2s3hydroxy45methyl134thiadiazol2ylsulfanyl1phenyl2butyl4methylbenzenesulfonamide
AT wardelljamesl n2s3hydroxy45methyl134thiadiazol2ylsulfanyl1phenyl2butyl4methylbenzenesulfonamide
AT wardellsolangemsv n2s3hydroxy45methyl134thiadiazol2ylsulfanyl1phenyl2butyl4methylbenzenesulfonamide
AT tiekinkedwardrt n2s3hydroxy45methyl134thiadiazol2ylsulfanyl1phenyl2butyl4methylbenzenesulfonamide

Ejemplares similares