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N-Methyl-l-leucyl-l-leucine hydrochloride monohydrate
In the title compound C(13)H(27)N(2)O(3) (+)·Cl(−)·H(2)O, obtained by deprotecting the amino and carboxyl groups of an intermediate in the synthesis of the cyclic pentapeptide Galaxamide, a number of hydrogen-bonding interactions occur including aminium N—H⋯Cl, amide–carboxyl N—H⋯O, water O—H⋯Cl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200702/ https://www.ncbi.nlm.nih.gov/pubmed/22058991 http://dx.doi.org/10.1107/S1600536811031126 |
| _version_ | 1782214730049388544 |
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| author | Lu, Tao Xu, Mu-Wu Liao, Xiao-Jian Xu, Shi-Hai |
| author_facet | Lu, Tao Xu, Mu-Wu Liao, Xiao-Jian Xu, Shi-Hai |
| author_sort | Lu, Tao |
| collection | PubMed |
| description | In the title compound C(13)H(27)N(2)O(3) (+)·Cl(−)·H(2)O, obtained by deprotecting the amino and carboxyl groups of an intermediate in the synthesis of the cyclic pentapeptide Galaxamide, a number of hydrogen-bonding interactions occur including aminium N—H⋯Cl, amide–carboxyl N—H⋯O, water O—H⋯Cl and carboxyl–water O—H⋯O associations. The aminium N—H⋯Cl⋯H—N bridging extensions give rise to zigzag chains extending along the a axis, the overall two-dimensional structure lying in the (110) plane. |
| format | Online Article Text |
| id | pubmed-3200702 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2011 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-32007022011-11-06 N-Methyl-l-leucyl-l-leucine hydrochloride monohydrate Lu, Tao Xu, Mu-Wu Liao, Xiao-Jian Xu, Shi-Hai Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound C(13)H(27)N(2)O(3) (+)·Cl(−)·H(2)O, obtained by deprotecting the amino and carboxyl groups of an intermediate in the synthesis of the cyclic pentapeptide Galaxamide, a number of hydrogen-bonding interactions occur including aminium N—H⋯Cl, amide–carboxyl N—H⋯O, water O—H⋯Cl and carboxyl–water O—H⋯O associations. The aminium N—H⋯Cl⋯H—N bridging extensions give rise to zigzag chains extending along the a axis, the overall two-dimensional structure lying in the (110) plane. International Union of Crystallography 2011-08-27 /pmc/articles/PMC3200702/ /pubmed/22058991 http://dx.doi.org/10.1107/S1600536811031126 Text en © Lu et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Lu, Tao Xu, Mu-Wu Liao, Xiao-Jian Xu, Shi-Hai N-Methyl-l-leucyl-l-leucine hydrochloride monohydrate |
| title |
N-Methyl-l-leucyl-l-leucine hydrochloride monohydrate |
| title_full |
N-Methyl-l-leucyl-l-leucine hydrochloride monohydrate |
| title_fullStr |
N-Methyl-l-leucyl-l-leucine hydrochloride monohydrate |
| title_full_unstemmed |
N-Methyl-l-leucyl-l-leucine hydrochloride monohydrate |
| title_short |
N-Methyl-l-leucyl-l-leucine hydrochloride monohydrate |
| title_sort | n-methyl-l-leucyl-l-leucine hydrochloride monohydrate |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200702/ https://www.ncbi.nlm.nih.gov/pubmed/22058991 http://dx.doi.org/10.1107/S1600536811031126 |
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