(E)-2-[4-(Diethyl­amino)­styr­yl]-1-methyl­pyridinium 4-chloro­benzene­sulfonate monohydrate

In the title hydrated mol­ecular salt, C(18)H(23)N(2) (+)·C(6)H(4)ClO(3)S(−)·H(2)O, which shows moderate biological activity against methicillin-resistant Staphylococcus aureus (MRSA), one ethyl group of the 2-[4-(diethyl­amino)­styr­yl]-1-methyl­pyridinium cation is disordered over two orientations...

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Autores principales: Fun, Hoong-Kun, Kaewmanee, Narissara, Chanawanno, Kullapa, Karalai, Chatchanok, Chantrapromma, Suchada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200709/
https://www.ncbi.nlm.nih.gov/pubmed/22059040
http://dx.doi.org/10.1107/S1600536811034258
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author Fun, Hoong-Kun
Kaewmanee, Narissara
Chanawanno, Kullapa
Karalai, Chatchanok
Chantrapromma, Suchada
author_facet Fun, Hoong-Kun
Kaewmanee, Narissara
Chanawanno, Kullapa
Karalai, Chatchanok
Chantrapromma, Suchada
author_sort Fun, Hoong-Kun
collection PubMed
description In the title hydrated mol­ecular salt, C(18)H(23)N(2) (+)·C(6)H(4)ClO(3)S(−)·H(2)O, which shows moderate biological activity against methicillin-resistant Staphylococcus aureus (MRSA), one ethyl group of the 2-[4-(diethyl­amino)­styr­yl]-1-methyl­pyridinium cation is disordered over two orientations in a 0.604 (13):0.396 (13) ratio. The main part of the cation is nearly planar with a dihedral angle of 4.50 (10)° between the pyridinium and benzene rings. In the crystal, the components are linked by O—H⋯O hydrogen bonds and C—H⋯O weak inter­actions. Aromatic π–π stacking inter­actions with centroid–centroid separations of 3.7363 (12) and 3.7490 (13) Å also occur.
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spelling pubmed-32007092011-11-06 (E)-2-[4-(Diethyl­amino)­styr­yl]-1-methyl­pyridinium 4-chloro­benzene­sulfonate monohydrate Fun, Hoong-Kun Kaewmanee, Narissara Chanawanno, Kullapa Karalai, Chatchanok Chantrapromma, Suchada Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title hydrated mol­ecular salt, C(18)H(23)N(2) (+)·C(6)H(4)ClO(3)S(−)·H(2)O, which shows moderate biological activity against methicillin-resistant Staphylococcus aureus (MRSA), one ethyl group of the 2-[4-(diethyl­amino)­styr­yl]-1-methyl­pyridinium cation is disordered over two orientations in a 0.604 (13):0.396 (13) ratio. The main part of the cation is nearly planar with a dihedral angle of 4.50 (10)° between the pyridinium and benzene rings. In the crystal, the components are linked by O—H⋯O hydrogen bonds and C—H⋯O weak inter­actions. Aromatic π–π stacking inter­actions with centroid–centroid separations of 3.7363 (12) and 3.7490 (13) Å also occur. International Union of Crystallography 2011-08-27 /pmc/articles/PMC3200709/ /pubmed/22059040 http://dx.doi.org/10.1107/S1600536811034258 Text en © Fun et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Kaewmanee, Narissara
Chanawanno, Kullapa
Karalai, Chatchanok
Chantrapromma, Suchada
(E)-2-[4-(Diethyl­amino)­styr­yl]-1-methyl­pyridinium 4-chloro­benzene­sulfonate monohydrate
title (E)-2-[4-(Diethyl­amino)­styr­yl]-1-methyl­pyridinium 4-chloro­benzene­sulfonate monohydrate
title_full (E)-2-[4-(Diethyl­amino)­styr­yl]-1-methyl­pyridinium 4-chloro­benzene­sulfonate monohydrate
title_fullStr (E)-2-[4-(Diethyl­amino)­styr­yl]-1-methyl­pyridinium 4-chloro­benzene­sulfonate monohydrate
title_full_unstemmed (E)-2-[4-(Diethyl­amino)­styr­yl]-1-methyl­pyridinium 4-chloro­benzene­sulfonate monohydrate
title_short (E)-2-[4-(Diethyl­amino)­styr­yl]-1-methyl­pyridinium 4-chloro­benzene­sulfonate monohydrate
title_sort (e)-2-[4-(diethyl­amino)­styr­yl]-1-methyl­pyridinium 4-chloro­benzene­sulfonate monohydrate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200709/
https://www.ncbi.nlm.nih.gov/pubmed/22059040
http://dx.doi.org/10.1107/S1600536811034258
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