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2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)-5-meth­oxy­phenol

In the title quinazoline derivative, C(21)H(17)N(3)O(2), the benzimidazole unit makes dihedral angles of 8.29 (5) and 81.79 (5)° with the benzene rings of the quinazoline and meth­oxy­phenol units, respectively. The nitro­gen-containing six-membered ring adopts a half-chair conformation. In the crys...

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Autores principales: Eltayeb, Naser Eltaher, Teoh, Siang Guan, Chantrapromma, Suchada, Fun, Hoong-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200720/
https://www.ncbi.nlm.nih.gov/pubmed/22058999
http://dx.doi.org/10.1107/S1600536811034027
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author Eltayeb, Naser Eltaher
Teoh, Siang Guan
Chantrapromma, Suchada
Fun, Hoong-Kun
author_facet Eltayeb, Naser Eltaher
Teoh, Siang Guan
Chantrapromma, Suchada
Fun, Hoong-Kun
author_sort Eltayeb, Naser Eltaher
collection PubMed
description In the title quinazoline derivative, C(21)H(17)N(3)O(2), the benzimidazole unit makes dihedral angles of 8.29 (5) and 81.79 (5)° with the benzene rings of the quinazoline and meth­oxy­phenol units, respectively. The nitro­gen-containing six-membered ring adopts a half-chair conformation. In the crystal, the mol­ecules are linked through O—H⋯N hydrogen bonds into screw chains along the b axis; adjacent chains are further connected by N—H⋯O hydrogen bonds, thereby forming a two-dimensional network lying parallel to the bc plane. Weak C—H⋯π and π⋯π inter­actions with centroid–centroid distances of 3.5258 (8) and 3.7184 (7) Å are present and N⋯O [2.6816 (15) and 3.0519 (15) Å] short contacts also occur.
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spelling pubmed-32007202011-11-06 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)-5-meth­oxy­phenol Eltayeb, Naser Eltaher Teoh, Siang Guan Chantrapromma, Suchada Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title quinazoline derivative, C(21)H(17)N(3)O(2), the benzimidazole unit makes dihedral angles of 8.29 (5) and 81.79 (5)° with the benzene rings of the quinazoline and meth­oxy­phenol units, respectively. The nitro­gen-containing six-membered ring adopts a half-chair conformation. In the crystal, the mol­ecules are linked through O—H⋯N hydrogen bonds into screw chains along the b axis; adjacent chains are further connected by N—H⋯O hydrogen bonds, thereby forming a two-dimensional network lying parallel to the bc plane. Weak C—H⋯π and π⋯π inter­actions with centroid–centroid distances of 3.5258 (8) and 3.7184 (7) Å are present and N⋯O [2.6816 (15) and 3.0519 (15) Å] short contacts also occur. International Union of Crystallography 2011-08-27 /pmc/articles/PMC3200720/ /pubmed/22058999 http://dx.doi.org/10.1107/S1600536811034027 Text en © Eltayeb et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Eltayeb, Naser Eltaher
Teoh, Siang Guan
Chantrapromma, Suchada
Fun, Hoong-Kun
2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)-5-meth­oxy­phenol
title 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)-5-meth­oxy­phenol
title_full 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)-5-meth­oxy­phenol
title_fullStr 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)-5-meth­oxy­phenol
title_full_unstemmed 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)-5-meth­oxy­phenol
title_short 2-(5,6-Dihydro­benzimidazo[1,2-c]quinazolin-6-yl)-5-meth­oxy­phenol
title_sort 2-(5,6-dihydro­benzimidazo[1,2-c]quinazolin-6-yl)-5-meth­oxy­phenol
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200720/
https://www.ncbi.nlm.nih.gov/pubmed/22058999
http://dx.doi.org/10.1107/S1600536811034027
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