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2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol
In the title quinazoline derivative, C(21)H(17)N(3)O(2), the benzimidazole unit makes dihedral angles of 8.29 (5) and 81.79 (5)° with the benzene rings of the quinazoline and methoxyphenol units, respectively. The nitrogen-containing six-membered ring adopts a half-chair conformation. In the crys...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200720/ https://www.ncbi.nlm.nih.gov/pubmed/22058999 http://dx.doi.org/10.1107/S1600536811034027 |
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author | Eltayeb, Naser Eltaher Teoh, Siang Guan Chantrapromma, Suchada Fun, Hoong-Kun |
author_facet | Eltayeb, Naser Eltaher Teoh, Siang Guan Chantrapromma, Suchada Fun, Hoong-Kun |
author_sort | Eltayeb, Naser Eltaher |
collection | PubMed |
description | In the title quinazoline derivative, C(21)H(17)N(3)O(2), the benzimidazole unit makes dihedral angles of 8.29 (5) and 81.79 (5)° with the benzene rings of the quinazoline and methoxyphenol units, respectively. The nitrogen-containing six-membered ring adopts a half-chair conformation. In the crystal, the molecules are linked through O—H⋯N hydrogen bonds into screw chains along the b axis; adjacent chains are further connected by N—H⋯O hydrogen bonds, thereby forming a two-dimensional network lying parallel to the bc plane. Weak C—H⋯π and π⋯π interactions with centroid–centroid distances of 3.5258 (8) and 3.7184 (7) Å are present and N⋯O [2.6816 (15) and 3.0519 (15) Å] short contacts also occur. |
format | Online Article Text |
id | pubmed-3200720 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-32007202011-11-06 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol Eltayeb, Naser Eltaher Teoh, Siang Guan Chantrapromma, Suchada Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title quinazoline derivative, C(21)H(17)N(3)O(2), the benzimidazole unit makes dihedral angles of 8.29 (5) and 81.79 (5)° with the benzene rings of the quinazoline and methoxyphenol units, respectively. The nitrogen-containing six-membered ring adopts a half-chair conformation. In the crystal, the molecules are linked through O—H⋯N hydrogen bonds into screw chains along the b axis; adjacent chains are further connected by N—H⋯O hydrogen bonds, thereby forming a two-dimensional network lying parallel to the bc plane. Weak C—H⋯π and π⋯π interactions with centroid–centroid distances of 3.5258 (8) and 3.7184 (7) Å are present and N⋯O [2.6816 (15) and 3.0519 (15) Å] short contacts also occur. International Union of Crystallography 2011-08-27 /pmc/articles/PMC3200720/ /pubmed/22058999 http://dx.doi.org/10.1107/S1600536811034027 Text en © Eltayeb et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Eltayeb, Naser Eltaher Teoh, Siang Guan Chantrapromma, Suchada Fun, Hoong-Kun 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol |
title | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol |
title_full | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol |
title_fullStr | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol |
title_full_unstemmed | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol |
title_short | 2-(5,6-Dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol |
title_sort | 2-(5,6-dihydrobenzimidazo[1,2-c]quinazolin-6-yl)-5-methoxyphenol |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200720/ https://www.ncbi.nlm.nih.gov/pubmed/22058999 http://dx.doi.org/10.1107/S1600536811034027 |
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