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3,3,4,4-Tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine
The asymmetric unit of the title compound, C(14)H(12)F(8)N(2), contains one tetrafluoropyrrolidine system and one half-molecule of benzene; the latter, together with a second heterocyclic unit, are completed by symmetry, with a twofold crystallographic axis crossing through both the middle of the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200749/ https://www.ncbi.nlm.nih.gov/pubmed/22065017 http://dx.doi.org/10.1107/S1600536811033757 |
Sumario: | The asymmetric unit of the title compound, C(14)H(12)F(8)N(2), contains one tetrafluoropyrrolidine system and one half-molecule of benzene; the latter, together with a second heterocyclic unit, are completed by symmetry, with a twofold crystallographic axis crossing through both the middle of the bond between the C atoms bearing the heterocyclic rings and the opposite C—C bonds of the whole benzene molecule. The pyrrolidine ring shows an envelope conformation with the apex at the N atom. The dihedral angle between the least-squares plane of this ring and the benzene ring is 36.9 (5)°. There are intramolecular C—H⋯N interactions generating S(6) ring motifs. In the crystal structure, the molecules are linked by C—H⋯F interactions, forming chains parallel to [010]. |
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