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3,3,4,4-Tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine
The asymmetric unit of the title compound, C(14)H(12)F(8)N(2), contains one tetrafluoropyrrolidine system and one half-molecule of benzene; the latter, together with a second heterocyclic unit, are completed by symmetry, with a twofold crystallographic axis crossing through both the middle of the...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200749/ https://www.ncbi.nlm.nih.gov/pubmed/22065017 http://dx.doi.org/10.1107/S1600536811033757 |
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author | Wang, Jin Zhong, Jun-Wen Liu, Pei-Lian Cao, Wan-Wan Zeng, Zhuo |
author_facet | Wang, Jin Zhong, Jun-Wen Liu, Pei-Lian Cao, Wan-Wan Zeng, Zhuo |
author_sort | Wang, Jin |
collection | PubMed |
description | The asymmetric unit of the title compound, C(14)H(12)F(8)N(2), contains one tetrafluoropyrrolidine system and one half-molecule of benzene; the latter, together with a second heterocyclic unit, are completed by symmetry, with a twofold crystallographic axis crossing through both the middle of the bond between the C atoms bearing the heterocyclic rings and the opposite C—C bonds of the whole benzene molecule. The pyrrolidine ring shows an envelope conformation with the apex at the N atom. The dihedral angle between the least-squares plane of this ring and the benzene ring is 36.9 (5)°. There are intramolecular C—H⋯N interactions generating S(6) ring motifs. In the crystal structure, the molecules are linked by C—H⋯F interactions, forming chains parallel to [010]. |
format | Online Article Text |
id | pubmed-3200749 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-32007492011-11-06 3,3,4,4-Tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine Wang, Jin Zhong, Jun-Wen Liu, Pei-Lian Cao, Wan-Wan Zeng, Zhuo Acta Crystallogr Sect E Struct Rep Online Organic Papers The asymmetric unit of the title compound, C(14)H(12)F(8)N(2), contains one tetrafluoropyrrolidine system and one half-molecule of benzene; the latter, together with a second heterocyclic unit, are completed by symmetry, with a twofold crystallographic axis crossing through both the middle of the bond between the C atoms bearing the heterocyclic rings and the opposite C—C bonds of the whole benzene molecule. The pyrrolidine ring shows an envelope conformation with the apex at the N atom. The dihedral angle between the least-squares plane of this ring and the benzene ring is 36.9 (5)°. There are intramolecular C—H⋯N interactions generating S(6) ring motifs. In the crystal structure, the molecules are linked by C—H⋯F interactions, forming chains parallel to [010]. International Union of Crystallography 2011-08-27 /pmc/articles/PMC3200749/ /pubmed/22065017 http://dx.doi.org/10.1107/S1600536811033757 Text en © Wang et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Wang, Jin Zhong, Jun-Wen Liu, Pei-Lian Cao, Wan-Wan Zeng, Zhuo 3,3,4,4-Tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine |
title | 3,3,4,4-Tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine |
title_full | 3,3,4,4-Tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine |
title_fullStr | 3,3,4,4-Tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine |
title_full_unstemmed | 3,3,4,4-Tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine |
title_short | 3,3,4,4-Tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine |
title_sort | 3,3,4,4-tetrafluoro-1-[2-(3,3,4,4-tetrafluoropyrrolidin-1-yl)phenyl]pyrrolidine |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200749/ https://www.ncbi.nlm.nih.gov/pubmed/22065017 http://dx.doi.org/10.1107/S1600536811033757 |
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