Cargando…

3,3,4,4-Tetra­fluoro-1-[2-(3,3,4,4-tetra­fluoro­pyrrolidin-1-yl)phen­yl]pyrrolidine

The asymmetric unit of the title compound, C(14)H(12)F(8)N(2), contains one tetra­fluoro­pyrrolidine system and one half-mol­ecule of benzene; the latter, together with a second heterocyclic unit, are completed by symmetry, with a twofold crystallographic axis crossing through both the middle of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Jin, Zhong, Jun-Wen, Liu, Pei-Lian, Cao, Wan-Wan, Zeng, Zhuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200749/
https://www.ncbi.nlm.nih.gov/pubmed/22065017
http://dx.doi.org/10.1107/S1600536811033757
_version_ 1782214740857061376
author Wang, Jin
Zhong, Jun-Wen
Liu, Pei-Lian
Cao, Wan-Wan
Zeng, Zhuo
author_facet Wang, Jin
Zhong, Jun-Wen
Liu, Pei-Lian
Cao, Wan-Wan
Zeng, Zhuo
author_sort Wang, Jin
collection PubMed
description The asymmetric unit of the title compound, C(14)H(12)F(8)N(2), contains one tetra­fluoro­pyrrolidine system and one half-mol­ecule of benzene; the latter, together with a second heterocyclic unit, are completed by symmetry, with a twofold crystallographic axis crossing through both the middle of the bond between the C atoms bearing the heterocyclic rings and the opposite C—C bonds of the whole benzene mol­ecule. The pyrrolidine ring shows an envelope conformation with the apex at the N atom. The dihedral angle between the least-squares plane of this ring and the benzene ring is 36.9 (5)°. There are intra­molecular C—H⋯N inter­actions generating S(6) ring motifs. In the crystal structure, the mol­ecules are linked by C—H⋯F inter­actions, forming chains parallel to [010].
format Online
Article
Text
id pubmed-3200749
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher International Union of Crystallography
record_format MEDLINE/PubMed
spelling pubmed-32007492011-11-06 3,3,4,4-Tetra­fluoro-1-[2-(3,3,4,4-tetra­fluoro­pyrrolidin-1-yl)phen­yl]pyrrolidine Wang, Jin Zhong, Jun-Wen Liu, Pei-Lian Cao, Wan-Wan Zeng, Zhuo Acta Crystallogr Sect E Struct Rep Online Organic Papers The asymmetric unit of the title compound, C(14)H(12)F(8)N(2), contains one tetra­fluoro­pyrrolidine system and one half-mol­ecule of benzene; the latter, together with a second heterocyclic unit, are completed by symmetry, with a twofold crystallographic axis crossing through both the middle of the bond between the C atoms bearing the heterocyclic rings and the opposite C—C bonds of the whole benzene mol­ecule. The pyrrolidine ring shows an envelope conformation with the apex at the N atom. The dihedral angle between the least-squares plane of this ring and the benzene ring is 36.9 (5)°. There are intra­molecular C—H⋯N inter­actions generating S(6) ring motifs. In the crystal structure, the mol­ecules are linked by C—H⋯F inter­actions, forming chains parallel to [010]. International Union of Crystallography 2011-08-27 /pmc/articles/PMC3200749/ /pubmed/22065017 http://dx.doi.org/10.1107/S1600536811033757 Text en © Wang et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, Jin
Zhong, Jun-Wen
Liu, Pei-Lian
Cao, Wan-Wan
Zeng, Zhuo
3,3,4,4-Tetra­fluoro-1-[2-(3,3,4,4-tetra­fluoro­pyrrolidin-1-yl)phen­yl]pyrrolidine
title 3,3,4,4-Tetra­fluoro-1-[2-(3,3,4,4-tetra­fluoro­pyrrolidin-1-yl)phen­yl]pyrrolidine
title_full 3,3,4,4-Tetra­fluoro-1-[2-(3,3,4,4-tetra­fluoro­pyrrolidin-1-yl)phen­yl]pyrrolidine
title_fullStr 3,3,4,4-Tetra­fluoro-1-[2-(3,3,4,4-tetra­fluoro­pyrrolidin-1-yl)phen­yl]pyrrolidine
title_full_unstemmed 3,3,4,4-Tetra­fluoro-1-[2-(3,3,4,4-tetra­fluoro­pyrrolidin-1-yl)phen­yl]pyrrolidine
title_short 3,3,4,4-Tetra­fluoro-1-[2-(3,3,4,4-tetra­fluoro­pyrrolidin-1-yl)phen­yl]pyrrolidine
title_sort 3,3,4,4-tetra­fluoro-1-[2-(3,3,4,4-tetra­fluoro­pyrrolidin-1-yl)phen­yl]pyrrolidine
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200749/
https://www.ncbi.nlm.nih.gov/pubmed/22065017
http://dx.doi.org/10.1107/S1600536811033757
work_keys_str_mv AT wangjin 3344tetrafluoro123344tetrafluoropyrrolidin1ylphenylpyrrolidine
AT zhongjunwen 3344tetrafluoro123344tetrafluoropyrrolidin1ylphenylpyrrolidine
AT liupeilian 3344tetrafluoro123344tetrafluoropyrrolidin1ylphenylpyrrolidine
AT caowanwan 3344tetrafluoro123344tetrafluoropyrrolidin1ylphenylpyrrolidine
AT zengzhuo 3344tetrafluoro123344tetrafluoropyrrolidin1ylphenylpyrrolidine