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Bis[N-cyclohexyl-1-(2-{1-[(cyclohexyl­amino)carbonyl]cyclohexyl}-3,5-dioxo-1,2-oxazolidin-4-yl)cyclopentanecarbox­amide] monohydrate

The reaction of cyclo­hexyl isocyanide and alkyl­idene Meldrum’s acid (systematic name 2,2-dimethyl-1,3-dioxane-4,6-dione) in the presence of cyclo­hexyl ketoxime and dichloro­methane as solvent resulted in the title compound, 2C(28)H(43)N(3)O(5)·H(2)O. One methyl­ene group of the cyclo­pentane ring...

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Detalles Bibliográficos
Autores principales: Sheikhhosseini, Enayatollah, Vafadarnejad, Fahime, Habibi, Azizollah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200895/
https://www.ncbi.nlm.nih.gov/pubmed/22058907
http://dx.doi.org/10.1107/S1600536811028868
Descripción
Sumario:The reaction of cyclo­hexyl isocyanide and alkyl­idene Meldrum’s acid (systematic name 2,2-dimethyl-1,3-dioxane-4,6-dione) in the presence of cyclo­hexyl ketoxime and dichloro­methane as solvent resulted in the title compound, 2C(28)H(43)N(3)O(5)·H(2)O. One methyl­ene group of the cyclo­pentane ring was found to be disordered and was refined with occupancies 0.75:0.25. Intra­molecular N—H⋯O hydrogen bonds occur. The crystal structure is stabilized by inter­molecular N—H⋯O and O—H⋯O hydrogen bonds.