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Bis[N-cyclohexyl-1-(2-{1-[(cyclohexylamino)carbonyl]cyclohexyl}-3,5-dioxo-1,2-oxazolidin-4-yl)cyclopentanecarboxamide] monohydrate
The reaction of cyclohexyl isocyanide and alkylidene Meldrum’s acid (systematic name 2,2-dimethyl-1,3-dioxane-4,6-dione) in the presence of cyclohexyl ketoxime and dichloromethane as solvent resulted in the title compound, 2C(28)H(43)N(3)O(5)·H(2)O. One methylene group of the cyclopentane ring...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3200895/ https://www.ncbi.nlm.nih.gov/pubmed/22058907 http://dx.doi.org/10.1107/S1600536811028868 |
Sumario: | The reaction of cyclohexyl isocyanide and alkylidene Meldrum’s acid (systematic name 2,2-dimethyl-1,3-dioxane-4,6-dione) in the presence of cyclohexyl ketoxime and dichloromethane as solvent resulted in the title compound, 2C(28)H(43)N(3)O(5)·H(2)O. One methylene group of the cyclopentane ring was found to be disordered and was refined with occupancies 0.75:0.25. Intramolecular N—H⋯O hydrogen bonds occur. The crystal structure is stabilized by intermolecular N—H⋯O and O—H⋯O hydrogen bonds. |
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