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Directed ortho,ortho'-dimetalation of hydrobenzoin: Rapid access to hydrobenzoin derivatives useful for asymmetric synthesis

A variety of ortho,ortho'-disubstituted hydrobenzoin derivatives are readily accessible through a directed ortho,ortho'-dimetalation strategy in which the alcohol functions in hydrobenzoin are deprotonated by n-BuLi and the resulting lithium benzyl alkoxides serve as directed metalation gr...

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Detalles Bibliográficos
Autores principales: Cho, Inhee, Meimetis, Labros, Belding, Lee, Katz, Michael J, Dudding, Travis, Britton, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201044/
https://www.ncbi.nlm.nih.gov/pubmed/22043241
http://dx.doi.org/10.3762/bjoc.7.154

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