PEG-embedded KBr(3): A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines

PEG-embedded potassium tribromide ([K(+)PEG]Br(3)(−)) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester. At the end of the reaction the [K(+)PEG]Br(3)(−)...

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Detalles Bibliográficos
Autores principales: Verma, Sanny, Jain, Suman L, Sain, Bir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201047/
https://www.ncbi.nlm.nih.gov/pubmed/22043244
http://dx.doi.org/10.3762/bjoc.7.157
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author Verma, Sanny
Jain, Suman L
Sain, Bir
author_facet Verma, Sanny
Jain, Suman L
Sain, Bir
author_sort Verma, Sanny
collection PubMed
description PEG-embedded potassium tribromide ([K(+)PEG]Br(3)(−)) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester. At the end of the reaction the [K(+)PEG]Br(3)(−) was readily regenerated from the reaction mixture by treating the residue containing [K(+)PEG]Br(−) with molecular bromine.
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spelling pubmed-32010472011-10-31 PEG-embedded KBr(3): A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines Verma, Sanny Jain, Suman L Sain, Bir Beilstein J Org Chem Full Research Paper PEG-embedded potassium tribromide ([K(+)PEG]Br(3)(−)) was found to be an efficient and recyclable catalyst for the synthesis of functionalized piperidines in high yields in a one step, three component coupling between aldehyde, amine and β-keto ester. At the end of the reaction the [K(+)PEG]Br(3)(−) was readily regenerated from the reaction mixture by treating the residue containing [K(+)PEG]Br(−) with molecular bromine. Beilstein-Institut 2011-09-28 /pmc/articles/PMC3201047/ /pubmed/22043244 http://dx.doi.org/10.3762/bjoc.7.157 Text en Copyright © 2011, Verma et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Full Research Paper
Verma, Sanny
Jain, Suman L
Sain, Bir
PEG-embedded KBr(3): A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines
title PEG-embedded KBr(3): A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines
title_full PEG-embedded KBr(3): A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines
title_fullStr PEG-embedded KBr(3): A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines
title_full_unstemmed PEG-embedded KBr(3): A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines
title_short PEG-embedded KBr(3): A recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines
title_sort peg-embedded kbr(3): a recyclable catalyst for multicomponent coupling reaction for the efficient synthesis of functionalized piperidines
topic Full Research Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201047/
https://www.ncbi.nlm.nih.gov/pubmed/22043244
http://dx.doi.org/10.3762/bjoc.7.157
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AT sainbir pegembeddedkbr3arecyclablecatalystformulticomponentcouplingreactionfortheefficientsynthesisoffunctionalizedpiperidines

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