Cargando…
Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids
This paper reviews the current trends in the combined use of supported catalytic systems, either on solid supports or in liquid phases and supercritical fluids (scFs), to develop selective and enantioselective chemical transformations under continuous and semi-continuous flow conditions. The results...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201049/ https://www.ncbi.nlm.nih.gov/pubmed/22043246 http://dx.doi.org/10.3762/bjoc.7.159 |
_version_ | 1782214808296226816 |
---|---|
author | Burguete, M Isabel García-Verdugo, Eduardo Luis, Santiago V |
author_facet | Burguete, M Isabel García-Verdugo, Eduardo Luis, Santiago V |
author_sort | Burguete, M Isabel |
collection | PubMed |
description | This paper reviews the current trends in the combined use of supported catalytic systems, either on solid supports or in liquid phases and supercritical fluids (scFs), to develop selective and enantioselective chemical transformations under continuous and semi-continuous flow conditions. The results presented have been selected to highlight how the combined use of those two elements can contribute to: (i) Significant improvements in productivity as a result of the enhanced diffusion of substrates and reagents through the interfaces favored by the scF phase; (ii) the long term stability of the catalytic systems, which also contributes to the improvement of the final productivity, as the use of an appropriate immobilization strategy facilitates catalyst isolation and reuse; (iii) the development of highly efficient selective or, when applicable, enantioselective chemical transformations. Although the examples reported in the literature and considered in this review are currently confined to a limited number of fields, a significant development in this area can be envisaged for the near future due to the clear advantages of these systems over the conventional ones. |
format | Online Article Text |
id | pubmed-3201049 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Beilstein-Institut |
record_format | MEDLINE/PubMed |
spelling | pubmed-32010492011-10-31 Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids Burguete, M Isabel García-Verdugo, Eduardo Luis, Santiago V Beilstein J Org Chem Review This paper reviews the current trends in the combined use of supported catalytic systems, either on solid supports or in liquid phases and supercritical fluids (scFs), to develop selective and enantioselective chemical transformations under continuous and semi-continuous flow conditions. The results presented have been selected to highlight how the combined use of those two elements can contribute to: (i) Significant improvements in productivity as a result of the enhanced diffusion of substrates and reagents through the interfaces favored by the scF phase; (ii) the long term stability of the catalytic systems, which also contributes to the improvement of the final productivity, as the use of an appropriate immobilization strategy facilitates catalyst isolation and reuse; (iii) the development of highly efficient selective or, when applicable, enantioselective chemical transformations. Although the examples reported in the literature and considered in this review are currently confined to a limited number of fields, a significant development in this area can be envisaged for the near future due to the clear advantages of these systems over the conventional ones. Beilstein-Institut 2011-09-30 /pmc/articles/PMC3201049/ /pubmed/22043246 http://dx.doi.org/10.3762/bjoc.7.159 Text en Copyright © 2011, Burguete et al. https://creativecommons.org/licenses/by/2.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms) |
spellingShingle | Review Burguete, M Isabel García-Verdugo, Eduardo Luis, Santiago V Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids |
title | Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids |
title_full | Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids |
title_fullStr | Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids |
title_full_unstemmed | Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids |
title_short | Efficient and selective chemical transformations under flow conditions: The combination of supported catalysts and supercritical fluids |
title_sort | efficient and selective chemical transformations under flow conditions: the combination of supported catalysts and supercritical fluids |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201049/ https://www.ncbi.nlm.nih.gov/pubmed/22043246 http://dx.doi.org/10.3762/bjoc.7.159 |
work_keys_str_mv | AT burguetemisabel efficientandselectivechemicaltransformationsunderflowconditionsthecombinationofsupportedcatalystsandsupercriticalfluids AT garciaverdugoeduardo efficientandselectivechemicaltransformationsunderflowconditionsthecombinationofsupportedcatalystsandsupercriticalfluids AT luissantiagov efficientandselectivechemicaltransformationsunderflowconditionsthecombinationofsupportedcatalystsandsupercriticalfluids |