Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

Fumarates improve multiple sclerosis (MS) and psoriasis, two diseases in which both IL-12 and IL-23 promote pathogenic T helper (Th) cell differentiation. However, both diseases show opposing responses to most established therapies. First, we show in humans that fumarate treatment induces IL-4–produ...

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Detalles Bibliográficos
Autores principales: Ghoreschi, Kamran, Brück, Jürgen, Kellerer, Christina, Deng, Caishu, Peng, Haiyan, Rothfuss, Oliver, Hussain, Rehana Z., Gocke, Anne R., Respa, Annedore, Glocova, Ivana, Valtcheva, Nadejda, Alexander, Eva, Feil, Susanne, Feil, Robert, Schulze-Osthoff, Klaus, Rupec, Rudolf A., Lovett-Racke, Amy E., Dringen, Ralf, Racke, Michael K., Röcken, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201195/
https://www.ncbi.nlm.nih.gov/pubmed/21987655
http://dx.doi.org/10.1084/jem.20100977

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