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Assembling defenses against therapy-resistant leukemic stem cells: Bcl6 joins the ranks
The resistance of leukemic stem cells in response to targeted therapies such as tyrosine kinase inhibitors (TKIs) relies on the cooperative activity of multiple signaling pathways and molecules, including TGFβ, AKT, and FOXO transcription factors (TFs). B cell lymphoma 6 (BCL6) is a transcriptional...
Autores principales: | Pellicano, Francesca, Holyoake, Tessa L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201197/ https://www.ncbi.nlm.nih.gov/pubmed/22025499 http://dx.doi.org/10.1084/jem.20112087 |
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