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Osteoclasts are dispensable for hematopoietic stem cell maintenance and mobilization

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Hematopoietic stem cells (HSCs) are maintained in a specific bone marrow (BM) niche in cavities formed by osteoclasts. Osteoclast-deficient mice are osteopetrotic and exhibit closed BM cavities. Osteoclast activity is inversely correlated with hematopoietic activity; however, how osteoclasts and the...

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Detalles Bibliográficos
Autores principales:	Miyamoto, Kana, Yoshida, Shigeyuki, Kawasumi, Miyuri, Hashimoto, Kazuaki, Kimura, Tokuhiro, Sato, Yuiko, Kobayashi, Tami, Miyauchi, Yoshiteru, Hoshi, Hiroko, Iwasaki, Ryotaro, Miyamoto, Hiroya, Hao, Wu, Morioka, Hideo, Chiba, Kazuhiro, Kobayashi, Takashi, Yasuda, Hisataka, Penninger, Josef M., Toyama, Yoshiaki, Suda, Toshio, Miyamoto, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2011
Materias:	Brief Definitive Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201203/ https://www.ncbi.nlm.nih.gov/pubmed/22006978 http://dx.doi.org/10.1084/jem.20101890

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