Tolerogenic function of Blimp-1 in dendritic cells

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Blimp-1 has been identified as a key regulator of plasma cell differentiation in B cells and effector/memory function in T cells. We demonstrate that Blimp-1 in dendritic cells (DCs) is required to maintain immune tolerance in female but not male mice. Female mice lacking Blimp-1 expression in DCs (...

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Detalles Bibliográficos
Autores principales: Kim, Sun Jung, Zou, Yong Rui, Goldstein, Jordan, Reizis, Boris, Diamond, Betty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201204/
https://www.ncbi.nlm.nih.gov/pubmed/21948081
http://dx.doi.org/10.1084/jem.20110658

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