The Th17 immune response is controlled by the Rel–RORγ–RORγT transcriptional axis

The Th17 cells use the retinoid-related orphan receptor-γ (Rorg or Rorc) to specify their differentiation and lineage-specific function. However, how Rorg is switched on during Th17 differentiation is unknown. We report here that c-Rel and RelA/p65 transcription factors drive Th17 differentiation by...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruan, Qingguo, Kameswaran, Vasumathi, Zhang, Yan, Zheng, Shijun, Sun, Jing, Wang, Junmei, DeVirgiliis, Jennifer, Liou, Hsiou-Chi, Beg, Amer A., Chen, Youhai H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201209/
https://www.ncbi.nlm.nih.gov/pubmed/22006976
http://dx.doi.org/10.1084/jem.20110462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201209/
https://www.ncbi.nlm.nih.gov/pubmed/22006976
http://dx.doi.org/10.1084/jem.20110462

Ejemplares similares