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rac-(6S)-6-Hydroxy-6-{2-[2-(propan-2-ylidene)hydrazinylidene]propyl}indolo[2,1-b]quinazolin-12(6H)-one
The chiral title compound, C(21)H(20)N(4)O(2), crystallizes as a racemic mixture. In the crystal, molecules form centrosymmetric π-overlapping dimers [interplanar distance = 3.338 (6) Å], which are further connected along the a axis forming centrosymmetric dimers via O—H⋯N hydrogen bonds. C—H⋯O in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201358/ https://www.ncbi.nlm.nih.gov/pubmed/22065467 http://dx.doi.org/10.1107/S1600536811037408 |
Sumario: | The chiral title compound, C(21)H(20)N(4)O(2), crystallizes as a racemic mixture. In the crystal, molecules form centrosymmetric π-overlapping dimers [interplanar distance = 3.338 (6) Å], which are further connected along the a axis forming centrosymmetric dimers via O—H⋯N hydrogen bonds. C—H⋯O interactions are also observed. The indolo[2,1-b]quinazoline group is somewhat bent, with a small dihedral angle of 6.3 (4)° between the plane of the quinazoline system and the plane of the benzene ring of the indole moiety. The C=N—N=C atoms of the azine group is oriented almost perpendicular [84.1 (2)°] to the mean plane of the quinazoline system. |
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