(4R)-4-(Biphenyl-4-yl)-7-chloro-1,2,3,4-tetra­hydro­quinoline

The title compound, C(21)H(18)ClN, was synthesized by an enanti­oselective Brønsted acid-catalysed transfer hydrogenation reaction. The six-membered heterocycle adopts a half-chair conformation. It has the biphenyl residue in an axial position. The two rings of the biphenyl residue are almost coplan...

Descripción completa

Detalles Bibliográficos
Autores principales: Theissmann, Thomas, Bolte, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201410/
https://www.ncbi.nlm.nih.gov/pubmed/22064825
http://dx.doi.org/10.1107/S160053681103830X
Descripción
Sumario:The title compound, C(21)H(18)ClN, was synthesized by an enanti­oselective Brønsted acid-catalysed transfer hydrogenation reaction. The six-membered heterocycle adopts a half-chair conformation. It has the biphenyl residue in an axial position. The two rings of the biphenyl residue are almost coplanar [dihedral angle = 2.65 (9)°]. The crystal packing is stabilized by N—H⋯Cl hydrogen bonds, which connect the mol­ecules into chains running along the a axis.

Ejemplares similares