2-(5-Bromo­pyridin-3-yl)-5-[3-(4,5,6,7-tetra­hydro­thieno[3,2-c]pyridine-5-ylsulfon­yl)thio­phen-2-yl]-1,3,4-oxa­diazole

In the title compound, C(18)H(13)BrN(4)O(3)S(3), the tetra­hydro­pyridine ring adopts a half-chair conformation with the central methyl­ene-C atom of the NCH(2)CH(2) unit at the flap. The dihedral angles between the tetra­hydro­pyridine ring and the pyridine and two thio­phene rings are 69.34 (13) 5...

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Autores principales: Fun, Hoong-Kun, Hemamalini, Madhukar, Rai, Sankappa, Isloor, A. M., Shetty, Prakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201536/
https://www.ncbi.nlm.nih.gov/pubmed/22058804
http://dx.doi.org/10.1107/S1600536811038529
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author Fun, Hoong-Kun
Hemamalini, Madhukar
Rai, Sankappa
Isloor, A. M.
Shetty, Prakash
author_facet Fun, Hoong-Kun
Hemamalini, Madhukar
Rai, Sankappa
Isloor, A. M.
Shetty, Prakash
author_sort Fun, Hoong-Kun
collection PubMed
description In the title compound, C(18)H(13)BrN(4)O(3)S(3), the tetra­hydro­pyridine ring adopts a half-chair conformation with the central methyl­ene-C atom of the NCH(2)CH(2) unit at the flap. The dihedral angles between the tetra­hydro­pyridine ring and the pyridine and two thio­phene rings are 69.34 (13) 5.66 (13) and 68.63 (13)°, respectively, while the dihedral angle between the 1,3,4-oxadiazole and tetra­hydro­pyridine rings is 54.76 (13)°. The mol­ecule is stabilized by an intra­molecular C—H⋯N inter­action. In the crystal, adjacent mol­ecules are connected via bifurcated C—H⋯(N,O) hydrogen bonds, forming a chain along the b axis.
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spelling pubmed-32015362011-11-06 2-(5-Bromo­pyridin-3-yl)-5-[3-(4,5,6,7-tetra­hydro­thieno[3,2-c]pyridine-5-ylsulfon­yl)thio­phen-2-yl]-1,3,4-oxa­diazole Fun, Hoong-Kun Hemamalini, Madhukar Rai, Sankappa Isloor, A. M. Shetty, Prakash Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(18)H(13)BrN(4)O(3)S(3), the tetra­hydro­pyridine ring adopts a half-chair conformation with the central methyl­ene-C atom of the NCH(2)CH(2) unit at the flap. The dihedral angles between the tetra­hydro­pyridine ring and the pyridine and two thio­phene rings are 69.34 (13) 5.66 (13) and 68.63 (13)°, respectively, while the dihedral angle between the 1,3,4-oxadiazole and tetra­hydro­pyridine rings is 54.76 (13)°. The mol­ecule is stabilized by an intra­molecular C—H⋯N inter­action. In the crystal, adjacent mol­ecules are connected via bifurcated C—H⋯(N,O) hydrogen bonds, forming a chain along the b axis. International Union of Crystallography 2011-09-30 /pmc/articles/PMC3201536/ /pubmed/22058804 http://dx.doi.org/10.1107/S1600536811038529 Text en © Fun et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Hemamalini, Madhukar
Rai, Sankappa
Isloor, A. M.
Shetty, Prakash
2-(5-Bromo­pyridin-3-yl)-5-[3-(4,5,6,7-tetra­hydro­thieno[3,2-c]pyridine-5-ylsulfon­yl)thio­phen-2-yl]-1,3,4-oxa­diazole
title 2-(5-Bromo­pyridin-3-yl)-5-[3-(4,5,6,7-tetra­hydro­thieno[3,2-c]pyridine-5-ylsulfon­yl)thio­phen-2-yl]-1,3,4-oxa­diazole
title_full 2-(5-Bromo­pyridin-3-yl)-5-[3-(4,5,6,7-tetra­hydro­thieno[3,2-c]pyridine-5-ylsulfon­yl)thio­phen-2-yl]-1,3,4-oxa­diazole
title_fullStr 2-(5-Bromo­pyridin-3-yl)-5-[3-(4,5,6,7-tetra­hydro­thieno[3,2-c]pyridine-5-ylsulfon­yl)thio­phen-2-yl]-1,3,4-oxa­diazole
title_full_unstemmed 2-(5-Bromo­pyridin-3-yl)-5-[3-(4,5,6,7-tetra­hydro­thieno[3,2-c]pyridine-5-ylsulfon­yl)thio­phen-2-yl]-1,3,4-oxa­diazole
title_short 2-(5-Bromo­pyridin-3-yl)-5-[3-(4,5,6,7-tetra­hydro­thieno[3,2-c]pyridine-5-ylsulfon­yl)thio­phen-2-yl]-1,3,4-oxa­diazole
title_sort 2-(5-bromo­pyridin-3-yl)-5-[3-(4,5,6,7-tetra­hydro­thieno[3,2-c]pyridine-5-ylsulfon­yl)thio­phen-2-yl]-1,3,4-oxa­diazole
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201536/
https://www.ncbi.nlm.nih.gov/pubmed/22058804
http://dx.doi.org/10.1107/S1600536811038529
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