2,2-Diethyl 4-methyl 5-(4-nitro­phen­yl)-4-phenyl­pyrrolidine-2,2,4-tricarboxyl­ate

The title compound, C(24)H(26)N(2)O(8), was synthesized by the cyclo­addition reaction of methyl 2-phenyl­acrylate, diethyl 2-amino­malonate and 4-nitro­benzaldehyde. The pyrrolidine ring exhibits an envelope conformation. The two benzene rings are located on opposite sides of the pyrrolidine ring a...

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Detalles Bibliográficos
Autor principal: He, Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201539/
https://www.ncbi.nlm.nih.gov/pubmed/22065547
http://dx.doi.org/10.1107/S1600536811036038
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author He, Long
author_facet He, Long
author_sort He, Long
collection PubMed
description The title compound, C(24)H(26)N(2)O(8), was synthesized by the cyclo­addition reaction of methyl 2-phenyl­acrylate, diethyl 2-amino­malonate and 4-nitro­benzaldehyde. The pyrrolidine ring exhibits an envelope conformation. The two benzene rings are located on opposite sides of the pyrrolidine ring and subtend a dihedral angle of 59.16 (14)°. The crystal packing is stabilized by N—H⋯O and weak C—H⋯O hydrogen bonding.
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spelling pubmed-32015392011-11-06 2,2-Diethyl 4-methyl 5-(4-nitro­phen­yl)-4-phenyl­pyrrolidine-2,2,4-tricarboxyl­ate He, Long Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(24)H(26)N(2)O(8), was synthesized by the cyclo­addition reaction of methyl 2-phenyl­acrylate, diethyl 2-amino­malonate and 4-nitro­benzaldehyde. The pyrrolidine ring exhibits an envelope conformation. The two benzene rings are located on opposite sides of the pyrrolidine ring and subtend a dihedral angle of 59.16 (14)°. The crystal packing is stabilized by N—H⋯O and weak C—H⋯O hydrogen bonding. International Union of Crystallography 2011-09-14 /pmc/articles/PMC3201539/ /pubmed/22065547 http://dx.doi.org/10.1107/S1600536811036038 Text en © Long He 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
He, Long
2,2-Diethyl 4-methyl 5-(4-nitro­phen­yl)-4-phenyl­pyrrolidine-2,2,4-tricarboxyl­ate
title 2,2-Diethyl 4-methyl 5-(4-nitro­phen­yl)-4-phenyl­pyrrolidine-2,2,4-tricarboxyl­ate
title_full 2,2-Diethyl 4-methyl 5-(4-nitro­phen­yl)-4-phenyl­pyrrolidine-2,2,4-tricarboxyl­ate
title_fullStr 2,2-Diethyl 4-methyl 5-(4-nitro­phen­yl)-4-phenyl­pyrrolidine-2,2,4-tricarboxyl­ate
title_full_unstemmed 2,2-Diethyl 4-methyl 5-(4-nitro­phen­yl)-4-phenyl­pyrrolidine-2,2,4-tricarboxyl­ate
title_short 2,2-Diethyl 4-methyl 5-(4-nitro­phen­yl)-4-phenyl­pyrrolidine-2,2,4-tricarboxyl­ate
title_sort 2,2-diethyl 4-methyl 5-(4-nitro­phen­yl)-4-phenyl­pyrrolidine-2,2,4-tricarboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201539/
https://www.ncbi.nlm.nih.gov/pubmed/22065547
http://dx.doi.org/10.1107/S1600536811036038
work_keys_str_mv AT helong 22diethyl4methyl54nitrophenyl4phenylpyrrolidine224tricarboxylate

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