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Towards computional specificity screening of DNA-binding proteins

DNA-binding proteins are key players in the regulation of gene expression and, hence, are essential for cell function. Chimeric proteins composed of DNA-binding domains and DNA modifying domains allow for precise genome manipulation. A key prerequisite is the specific recognition of a particular nuc...

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Detalles Bibliográficos
Autores principales:	Seeliger, Daniel, Buelens, Floris P., Goette, Maik, de Groot, Bert L., Grubmüller, Helmut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Computational Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201868/ https://www.ncbi.nlm.nih.gov/pubmed/21737424 http://dx.doi.org/10.1093/nar/gkr531

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