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Structural basis for the biological relevance of the invariant apical stem in IRES-mediated translation
RNA structure plays a fundamental role in internal initiation of translation. Picornavirus internal ribosome entry site (IRES) are long, efficient cis-acting elements that recruit the ribosome to internal mRNA sites. However, little is known about long-range constraints determining the IRES RNA stru...
Autores principales: | Fernández, Noemí, Fernandez-Miragall, Olga, Ramajo, Jorge, García-Sacristán, Ana, Bellora, Nicolás, Eyras, Eduardo, Briones, Carlos, Martínez-Salas, Encarnación |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201876/ https://www.ncbi.nlm.nih.gov/pubmed/21742761 http://dx.doi.org/10.1093/nar/gkr560 |
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