Reconstitution of a functional IS608 single-strand transpososome: role of non-canonical base pairing

Single-stranded (ss) transposition, a recently identified mechanism adopted by members of the widespread IS200/IS605 family of insertion sequences (IS), is catalysed by the transposase, TnpA. The transposase of IS608, recognizes subterminal imperfect palindromes (IP) at both IS ends and cleaves at s...

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Detalles Bibliográficos
Autores principales: He, Susu, Hickman, Alison B., Dyda, Fred, Johnson, Neil P., Chandler, Michael, Ton-Hoang, Bao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201880/
https://www.ncbi.nlm.nih.gov/pubmed/21745812
http://dx.doi.org/10.1093/nar/gkr566

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