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Advanced Glycation in macrophages induces intracellular accumulation of 7-ketocholesterol and total sterols by decreasing the expression of ABCA-1 and ABCG-1

BACKGROUND: Advanced glycation end products (AGE) alter lipid metabolism and reduce the macrophage expression of ABCA-1 and ABCG-1 which impairs the reverse cholesterol transport, a system that drives cholesterol from arterial wall macrophages to the liver, allowing its excretion into the bile and f...

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Detalles Bibliográficos
Autores principales:	Iborra, Rodrigo T, Machado-Lima, Adriana, Castilho, Gabriela, Nunes, Valeria S, Abdalla, Dulcinéia SP, Nakandakare, Edna R, Passarelli, Marisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201908/ https://www.ncbi.nlm.nih.gov/pubmed/21957962 http://dx.doi.org/10.1186/1476-511X-10-172

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