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Hepatitis B Virus Impairs TLR9 Expression and Function in Plasmacytoid Dendritic Cells
Plasmacytoid dendritic cells (pDCs) play a key role in detecting pathogens by producing large amounts of type I interferon (IFN) by sensing the presence of viral infections through the Toll-Like Receptor (TLR) pathway. TLR9 is a sensor of viral and bacterial DNA motifs and activates the IRF7 transcr...
Autores principales: | Vincent, Isabelle E., Zannetti, Claudia, Lucifora, Julie, Norder, Helene, Protzer, Ulrike, Hainaut, Pierre, Zoulim, Fabien, Tommasino, Massimo, Trépo, Christian, Hasan, Uzma, Chemin, Isabelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201951/ https://www.ncbi.nlm.nih.gov/pubmed/22046272 http://dx.doi.org/10.1371/journal.pone.0026315 |
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