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Adverse Events of Interferon Beta-1a: A Prospective Multi-Centre International ICH-GCP-Based CRO-Supported External Validation Study in Daily Practice
BACKGROUND: Due to methodological shortcomings the available post-registration data on the adverse events (AEs) occurring in interferon beta-1a (INFb-1a)-treated patients fail to adequately validate phase III data and only partially inform on safety in daily practice. We assessed AEs in relapsing re...
Autores principales: | Jongen, Peter Joseph, Sindic, Christian, Sanders, Evert, Hawkins, Stanley, Linssen, Wim, van Munster, Erik, Frequin, Stephan, Borm, George |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201962/ https://www.ncbi.nlm.nih.gov/pubmed/22046309 http://dx.doi.org/10.1371/journal.pone.0026568 |
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