Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency

In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. Because life-threatening disseminated BCG disease may occur in children with primary immunodeficiency, vaccination strategy against...

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Autores principales: Bacalhau, Sílvia, Freitas, Cristina, Valente, Rosalina, Barata, Deolinda, Neves, Conceição, Schäfer, Katrin, Lubatschofski, Annelie, Schulz, Ansgar, Neves, João Farela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202142/
https://www.ncbi.nlm.nih.gov/pubmed/22110512
http://dx.doi.org/10.1155/2011/527569
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author Bacalhau, Sílvia
Freitas, Cristina
Valente, Rosalina
Barata, Deolinda
Neves, Conceição
Schäfer, Katrin
Lubatschofski, Annelie
Schulz, Ansgar
Neves, João Farela
author_facet Bacalhau, Sílvia
Freitas, Cristina
Valente, Rosalina
Barata, Deolinda
Neves, Conceição
Schäfer, Katrin
Lubatschofski, Annelie
Schulz, Ansgar
Neves, João Farela
author_sort Bacalhau, Sílvia
collection PubMed
description In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. Because life-threatening disseminated BCG disease may occur in children with primary immunodeficiency, vaccination strategy against tuberculosis should be redefined in non-high-burden countries. We report the case of a patient with X-linked severe combined immunodeficiency (SCID) who developed disseminated BCG disease, highlighting the specific strategies adopted.
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spelling pubmed-32021422011-11-22 Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency Bacalhau, Sílvia Freitas, Cristina Valente, Rosalina Barata, Deolinda Neves, Conceição Schäfer, Katrin Lubatschofski, Annelie Schulz, Ansgar Neves, João Farela Case Rep Med Case Report In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. Because life-threatening disseminated BCG disease may occur in children with primary immunodeficiency, vaccination strategy against tuberculosis should be redefined in non-high-burden countries. We report the case of a patient with X-linked severe combined immunodeficiency (SCID) who developed disseminated BCG disease, highlighting the specific strategies adopted. Hindawi Publishing Corporation 2011 2011-10-24 /pmc/articles/PMC3202142/ /pubmed/22110512 http://dx.doi.org/10.1155/2011/527569 Text en Copyright © 2011 Sílvia Bacalhau et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Bacalhau, Sílvia
Freitas, Cristina
Valente, Rosalina
Barata, Deolinda
Neves, Conceição
Schäfer, Katrin
Lubatschofski, Annelie
Schulz, Ansgar
Neves, João Farela
Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency
title Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency
title_full Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency
title_fullStr Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency
title_full_unstemmed Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency
title_short Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency
title_sort successful handling of disseminated bcg disease in a child with severe combined immunodeficiency
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202142/
https://www.ncbi.nlm.nih.gov/pubmed/22110512
http://dx.doi.org/10.1155/2011/527569
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