Acquired Antibiotic Resistance Genes: An Overview

In this review an overview is given on antibiotic resistance (AR) mechanisms with special attentions to the AR genes described so far preceded by a short introduction on the discovery and mode of action of the different classes of antibiotics. As this review is only dealing with acquired resistance,...

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Detalles Bibliográficos
Autores principales: van Hoek, Angela H. A. M., Mevius, Dik, Guerra, Beatriz, Mullany, Peter, Roberts, Adam Paul, Aarts, Henk J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202223/
https://www.ncbi.nlm.nih.gov/pubmed/22046172
http://dx.doi.org/10.3389/fmicb.2011.00203
Descripción
Sumario:In this review an overview is given on antibiotic resistance (AR) mechanisms with special attentions to the AR genes described so far preceded by a short introduction on the discovery and mode of action of the different classes of antibiotics. As this review is only dealing with acquired resistance, attention is also paid to mobile genetic elements such as plasmids, transposons, and integrons, which are associated with AR genes, and involved in the dispersal of antimicrobial determinants between different bacteria.

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