Conditional deletion of epithelial IKKβ impairs alveolar formation through apoptosis and decreased VEGF expression during early mouse lung morphogenesis

BACKGROUND: Alveolar septation marks the beginning of the transition from the saccular to alveolar stage of lung development. Inflammation can disrupt this process and permanently impair alveolar formation resulting in alveolar hypoplasia as seen in bronchopulmonary dysplasia in preterm newborns. NF...

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Detalles Bibliográficos
Autores principales: Londhe, Vedang A, Maisonet, Tiffany M, Lopez, Benjamin, Jeng, Jade-Ming, Xiao, Jing, Li, Changgong, Minoo, Parviz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202236/
https://www.ncbi.nlm.nih.gov/pubmed/21985298
http://dx.doi.org/10.1186/1465-9921-12-134

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